Levobetaxolol

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Levobetaxolol
Levobetaxolol structure.svg
Levobetaxolol-fill.png
Systematic (IUPAC) name
(S)-1-[p-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(isopropylamino)-2-propanol hydrochloride
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
Pregnancy cat. C (US)
Legal status ?
Routes topical (ophthalmic)
Pharmacokinetic data
Half-life 20 hours
Identifiers
CAS number 93221-48-8 N
ATC code None
PubChem CID 60657
ChemSpider 54669 YesY
UNII 75O9XHA4TU YesY
ChEBI CHEBI:59254 YesY
ChEMBL CHEMBL1201274 N
Chemical data
Formula C18H29NO3 
Mol. mass 307.427 g/mol
 N (what is this?)  (verify)

Levobetaxolol is a drug used to lower the pressure in the eye in treating conditions such as glaucoma. It is typically marketed as a 0.5% ophthalmic solution of levobetaxolol hydrochloride under the trade name Betaxon. Levobetaxolol is a beta-adrenergic receptor inhibitor (beta blocker).

Effect[edit]

Levobetaxolol inhibits the beta-1-adrenergic receptor. When applied topically, it reduces intra-ocular pressure (IOP) by 16-23% depending on time of day and the individual. It is indicated for IOP reduction in patients with open-angle glaucoma or ocular hypertension. Levobetaxolol has fewer cardiovascular side effects than other beta blockers.

Contraindications and side effects[edit]

Levobetaxolol should not be used by people who have sinus bradycardia, atrioventricular block, cardiogenic shock, or overt cardiac failure.

The drug has been associated with bradycardia and hypertension.