Levobunolol

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Levobunolol
Levobunolol structural formulae.png
Systematic (IUPAC) name
(S)-5-{[3-(tert-butylamino)-2-hydroxypropyl]oxy}-3,4-dihydronaphthalen-1(2H)-one
Clinical data
Trade names Betagan
AHFS/Drugs.com monograph
MedlinePlus a686011
Pregnancy cat. C
Legal status -only (US)
Routes Topical (eye drops)
Pharmacokinetic data
Half-life 20 hours
Identifiers
CAS number 47141-42-4 YesY
ATC code S01ED03
PubChem CID 39468
DrugBank DB01210
ChemSpider 36089 YesY
UNII G6317AOI7K YesY
KEGG D08115 YesY
ChEBI CHEBI:6438 YesY
ChEMBL CHEMBL1201237 N
Chemical data
Formula C17H25NO3 
Mol. mass 291.385 g/mol
 N (what is this?)  (verify)

Levobunolol (AK-Beta, Liquifilm, Betegan) is a non-selective beta blocker. It is used topically to manage glaucoma.

References[edit]

  • Ishibashi T, Yokoi N, Kinoshita S (2003). "Comparison of the effects of topical levobunolol and timolol solution on the human ocular surface.". Cornea 22 (8): 709–15. doi:10.1097/00003226-200311000-00001. PMID 14576520. 
  • Ogasawara H, Yoshida A, Fujio N, Konno S, Ishiko S (1999). "[Effect of topical levobunolol on retinal, optic nerve head, and choroidal circulation in normal volunteers]". Nippon Ganka Gakkai Zasshi 103 (7): 544–50. PMID 10443129. 
  • Leung M, Grunwald J (1997). "Short-term effects of topical levobunolol on the human retinal circulation.". Eye 11 (3): 371–6. doi:10.1038/eye.1997.78. PMID 9373479.