Levomethamphetamine affects the central nervous system, although its effects are weaker and somewhat shorter than those of dextromethamphetamine, so it is not thought to possess the same addiction potential as that of racemicmethamphetamine or dextromethamphetamine. Among its few physiological effects are the vasoconstriction that makes it useful for nasal decongestion. The elimination half-life of levomethamphetamine is between 13.3 and 15 hours, whereas dextromethamphetamine has a half-life of about 10.5 hours.
^Melega, WP; Cho, AK; Schmitz, D; Kuczenski, R; Segal, DS (1999 Feb). "l-methamphetamine pharmacokinetics and pharmacodynamics for assessment of in vivo deprenyl-derived l-methamphetamine". The Journal of pharmacology and experimental therapeutics288 (2): 752–8. PMID9918585.Check date values in: |date= (help)
^ abMendelson, J; Uemura, N; Harris, D; Nath, RP; Fernandez, E; Jacob P, 3rd; Everhart, ET; Jones, RT (2006 Oct). "Human pharmacology of the methamphetamine stereoisomers". Clinical pharmacology and therapeutics80 (4): 403–20. doi:10.1016/j.clpt.2006.06.013. PMID17015058.Check date values in: |date= (help)
^Kuczenski, R; Segal, DS; Cho, AK; Melega, W (1995 Feb). "Hippocampus norepinephrine, caudate dopamine and serotonin, and behavioral responses to the stereoisomers of amphetamine and methamphetamine". The Journal of neuroscience : the official journal of the Society for Neuroscience15 (2): 1308–17. PMID7869099.Check date values in: |date= (help)
^Nonprescription Products to Avoid With Hypertension by W. Steven Pray, PhD, DPh, Bernhardt Professor, Nonprescription Products and Devices, College of Pharmacy, Southwestern Oklahoma State University, Weatherford, Oklahoma US Pharm. 2010;35(2):12-15. Posted 2/19/2010. Accessed via internet May 26, 2010. This new article incorporates the information formerly drawn from the article cited at the corresponding point in a previous version of this page, which article's former URL now forms a dead link.