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Lexatumumab ?
Monoclonal antibody
Type Whole antibody
Source Human
Target TRAIL-R2
Clinical data
Legal status
CAS number 845816-02-6 N
ATC code None
UNII 967Q0SJD77 YesY
KEGG D06611 YesY
Chemical data
Formula C6346H9832N1720O2002S42 
Mol. mass 143.6 kDa
 N (what is this?)  (verify)

Lexatumumab (also known as ETR2-ST01) is an experimental agonistic human monoclonal antibody against TRAIL-R2 (DR5, APO-2) undergoing clinical trials for the treatment of cancer.[1]

HGS-ETR2 antibodies were generated by HGS through a collaboration with Cambridge Antibody Technology.[2]


  1. ^ Statement on a Nonproprietary Name adopted by the USAN Council - Lexatumumab, American Medical Association.
  2. ^ http://www.hgsi.com/trail-receptor-antibodies-5.html