Chlordiazepoxide/clidinium bromide

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Chlordiazepoxide/clidinium bromide
Combination of
Chlordiazepoxide Anxiolytic
Clidinium bromide Antimuscarinic
Clinical data
AHFS/ monograph
MedlinePlus a601036
PubChem CID 3080646
ChemSpider 2338393 YesY
 YesY (what is this?)  (verify)

Chlordiazepoxide/clidinium bromide is a drug consisting of chlordiazepoxide and clidinium bromide and used to treat peptic ulcers, irritable bowel syndrome (IBS), and gastritis. It helps relieve stomach spasms, abdominal cramps, and anxiety related to gastric disorders.[1] Librax is a fixed ratio of these two medications and, as such, is not typically prescribed with an accompanying dosage, but rather how many capsules per day are to be taken. It comes as a capsule to be taken by mouth and is usually taken three or four times a day, before meals and at bedtime.[1] Chlordiazepoxide is an anti-anxiety medication belonging to the benzodiazepine class.[2] Its use in IBS is thought to be due to its calming ability for patients that have IBS symptoms that are worsened by anxiety. Clidinium bromide is a synthetic quaternary ammonium antimuscarinic,[3] a sub-class of a family of drugs known as anticholinergics. It works in IBS by decreasing gastrointestinal motility.

Chlordiazepoxide can be habit-forming. Tolerance may develop with long-term or excessive use, making this medication less effective. This medication must be taken regularly to be effective. Stopping the drug suddenly can worsen the condition and cause withdrawal symptoms (anxiousness, sleeplessness, and irritability).[1]


  1. ^ a b c "Librax". MedlinePlus: US National library of medicine. Retrieved 31 May 2013. 
  2. ^ MedScape - Chlordiazepoxide
  3. ^ MedScape - Clidinium

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