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Lipoflavonoid (or Lipo-flavonoid) is a proprietary, over-the-counter, nutrient formula created in 1961, by DSE Healthcare Solutions, which is claimed by the manufacturer to help combat tinnitus (sounds in the ears). It has not been approved by the Food and Drug Administration for this purpose.
Although Lipo-flavonoid is currently being marketed on the Internet and in televisions commercials specifically to relieve tinnitus, clinical studies of the product appearing in refereed journals address only its use in treating the relatively rare Meniere’s disease for which tinnitus may be one symptom. In the early 1960s, the Audiology Center of Walter Reed Hospital conducted a double-blind, placebo-controlled study of the effects of the lemon bioflavonoid active ingredient of Lipo-flavonoid on patients with hearing loss not associated with Meniere's Disease. None of the study participants who took bioflavonoid showed improvement. According to a Mayo Clinic article on tinnitus, there is little evidence that common alternative medicine treatments for tinnitus, including lipoflavonoids, are effective in relieving the condition.
Composition and effects
Lipoflavonoid is sold as a dietary supplement. It is composed of eriodictyol glycoside (a bioflavonoid found naturally in the peel of lemons) and the following vitamins: vitamin B6 and B12 (B complex), vitamin C, niacin, riboflavin, thiamine, choline, inositol, and pantothenic acid.
- "Lipo-flavonoid Testimonials and Reviews", manufacturers website
- "About Lipo-flavonoid: References", manufacturers website
- "Bioflavonoid Therapy in Sensorineural Hearing Loss: A Double-Blind Study", James E. Creston, Marion R. Gillespie, Alvin L. Larson, Arch Otolaryngol. 1965;82(2):159-165
- "Tinnitus: Alternative Medicine"
- "About Lipo-flavonoid: Lipo-flavonoid-Plus Ingredients", manufacturers website