List of Ebola outbreaks
|Articles related to the|
|Ebola virus epidemic in
|Ebola virus disease
Timeline of the epidemic
Responses to the epidemic
|Guinea • Liberia • Sierra Leone • Mali
Spain • United States
|List of Ebola outbreaks
1976 Zaire outbreak
2014 DR Congo outbreak
The International Committee on Taxonomy of Viruses currently recognizes five ebolaviruses: Ebola virus (EBOV), Sudan virus (SUDV), Reston virus (RESTV), Taï Forest virus (TAFV), and Bundibugyo virus (BDBV). Four of these viruses are known to cause Ebola virus disease (EVD) in humans, and the fifth, RESTV, has caused EVD in other primates.
Transmission between natural reservoirs and humans is rare, and outbreaks of Ebola virus disease are often traceable to a single case where an individual has handled the carcass of a gorilla, chimpanzee, or duiker. The virus then spreads person-to-person, especially within families, hospitals, and during some mortuary rituals where contact among individuals becomes more likely. Before outbreaks are confirmed in areas of weak surveillance on the local or regional levels, Ebola is often mistaken for malaria, typhoid fever, dysentery, influenza, or various bacterial infections which may be endemic to the region. Learning from failed responses, such as that to the 2000 Uganda outbreak, public health measures including the WHO's Global Outbreak and Response Network were instituted in areas at high risk. Field laboratories were established in order to confirm cases, instead of shipping samples to South Africa. Outbreaks are closely followed by the United States Centers for Disease Control and Prevention (Special Pathogens Branch) as well.
List of outbreaks
|Year||Country||Virus||Human cases||Human deaths||Case fatality rate||Description|
|1976||Sudan||SUDV||284||151||53%||Occurred in Nzara, Maridi and surrounding areas between June and November 1976. Mainly spread by personal contact in hospitals. Many medical care personnel were infected.|
Main article: Yambuku § Ebola outbreakOccurred in Yambuku and surrounding areas in August. Spread by personal contact and use of contaminated needles and syringes in hospitals/clinics.
|1976||United Kingdom||SUDV or EBOV[note 1]||1||0||N/A||Laboratory infection by accidental stick of contaminated needle.|
|1977||Zaire||EBOV||1||1||100%||Noted retroactively in the village of Tandala.|
|1979||Sudan||SUDV||34||22||65%||Occurred in Nzara, Maridi. Recurrent outbreak at the same site as the 1976 Sudan epidemic.|
|1989–1990||Philippines||RESTV||3[note 2]||0||N/A||High mortality among crab-eating macaques in a primate facility responsible for exporting animals in the USA. Three workers in the facility developed antibodies but did not get sick.|
|1989||United States||RESTV||0||0||N/A||RESTV was introduced into quarantine facilities in Virginia and Pennsylvania by monkeys imported from the Philippines. No human cases.|
|1990||United States||RESTV||4[note 3]||0||N/A||RESTV was introduced into quarantine facilities in Virginia and Texas by monkeys imported from the Philippines. Four humans developed antibodies but did not get sick.|
|1992||Italy||RESTV||0||0||N/A||RESTV was introduced into quarantine facilities in Siena by monkeys imported from the same facility in the Philippines as the 1989 and 1990 US outbreaks. No human cases.|
|1994||Gabon||EBOV||52||31||60%||Occurred in Mékouka and other gold-mining camps deep in the rain forest. Thought to be yellow fever until 1995.|
|1994||Côte d'Ivoire[note 4]||TAFV||1||0||N/A||First and thus far only recognition of TAFV. Approximately one week after conducting necropsies on infected western chimpanzees in Taï National Park, a scientist contracted the virus and developed symptoms similar to those of dengue fever. She was discharged from a Swiss hospital two weeks later, and fully recovered after six weeks.|
|1995||Zaire||EBOV||315||254||81%||Occurred in Kikwit and surrounding areas. Traced to index case-patient who worked in forest adjoining the city. Epidemic spread through families and hospitals.|
|1996||Gabon||EBOV||37||21||57%||Occurred in Mayibout area between January and April. A chimpanzee found dead in the forest was eaten by people hunting for food. Nineteen people who were involved in the butchery of the animal became ill; other cases occurred in family members.|
|1996–1997||Gabon||EBOV||60||45||75%||Occurred in Booué area with transport of patients to Libreville between July 1996 and January 1997. Index case-patient was a hunter who lived in a forest camp. Disease was spread by close contact with infected persons. A dead chimpanzee found in the forest at the time was determined to be infected.|
|1996||South Africa||EBOV||2||1||N/A||A medical professional traveled from Gabon to Johannesburg, South Africa, in October 1996 after having treated Ebola virus-infected patients. He was hospitalized, and the nurse that took care of him became infected and died.|
|1996||United States||RESTV||0||0||N/A||RESTV was introduced into a quarantine facility in Texas by monkeys imported from the same facility in the Philippines as the 1989 and 1990 US outbreaks. No human cases.|
|1996||Philippines||RESTV||0||0||N/A||RESTV was identified at a monkey export facility in the Philippines. No human cases.|
|2000–2001||Uganda||SUDV||425||224||53%||Occurred in Gulu, Masindi, and Mbarara districts of Uganda. The three greatest risks associated with Sudan virus infection were attending funerals of case-patients, having contact with case-patients in one's family, and providing medical care to case-patients without using adequate personal protective measures.|
Republic of the Congo
|EBOV||122||96||79%||Occurred over the border of Gabon and the Republic of the Congo between October 2001 and July 2002. First reported occurrence of Ebola virus disease in the Republic of the Congo.|
|2002–2003||Republic of the Congo||EBOV||143||128||90%||Occurred in the districts of Mbomo and Kéllé in Cuvette Ouest Département between December 2002 and April 2003.|
|2003||Republic of the Congo||EBOV||35||29||83%||Occurred in Mbomo and Mbandza villages located in Mbomo district, Cuvette Ouest Département, between November and December.|
|2004||Sudan||SUDV||17||7||41%||Occurred in Yambio county in Western Equatoria of southern Sudan. This outbreak was concurrent with an outbreak of measles in the same area, and several suspected EVD cases were later reclassified as measles cases.|
|2007||Democratic Republic of the Congo||EBOV||264||187||71%||Occurred in Kasai-Occidental Province. The outbreak was declared over on November 20. Last confirmed case on October 4 and last death on October 10.|
|2007–2008||Uganda||BDBV||149||37||25%||First recognition of BDBV. Occurred in Bundibugyo District in western Uganda between December 2007 and January 2008|
|2008||Philippines||RESTV||6[note 5]||0||N/A||First recognition of RESTV in pigs. Strain closely similar to earlier strains. Occurred in November. Six workers from the pig farm and slaughterhouse developed antibodies but did not become sick.|
|2008–2009||Democratic Republic of the Congo||EBOV||32||14||45%||Occurred in the Mweka and Luebo health zones of the Province of Kasai-Occidental between December 2008 and February 2009|
|2012||Uganda||SUDV||24||17||71%||Occurred in the Kibaale District between June and August.|
|2012||Democratic Republic of the Congo||BDBV||77||36||47%||Occurred in Province Orientale between June and November.|
Limited and local:
Main article: Ebola virus epidemic in West AfricaThe most severe Ebola outbreak recorded in regards to both the number of human cases and fatalities began in Guéckédou, Guinea, in December 2013, and spread abroad where it is still ongoing.
|2014||Democratic Republic of the Congo||EBOV||66||49||65%|| Declared over on 15 November 2014.|
- 2014 Ebola virus disease epidemic timeline
- Responses to the Ebola virus epidemic in West Africa
- Ebola virus epidemic in Guinea
- Ebola virus epidemic in Liberia
- Ebola virus epidemic in Sierra Leone
- Ebola virus outbreak in the United States
- Ebola virus disease cases in Spain
- Ebola virus disease in Mali
- List of Ebola patients
- List of epidemics
- The Centers for Disease Control chronology notes this infection as "Sudan virus", whereas the 1977 British Medical Journal (BMJ) article refers to it as "Ebola virus". In 1977, there was not yet a distinction between different ebolaviruses. The BMJ article only notes that the patient received "convalescent serum from the Sudan" following similar serum from Zaire.
- All three cases were asymptomatic.
- All four cases were asymptomatic.
- The single Ivorian case was repatriated to Switzerland for medical treatment.
- All six cases were asymptomatic.
- The estimated case fatality rate for this ongoing epidemic differs from the number of deaths divided by the number of cases due to the estimation method used. Current infections have not run their course, and the estimate may be poor if reporting is biased towards severe cases.
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