List of biotechnology companies

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A biotechnology company is a company whose products or services primarily use biotechnology methods for their production, design or delivery. The United Nations Convention on Biological Diversity defines 'biotechnology' as: "Any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use."[1] In other words, biotechology can be defined as the mere application of technical advances in life science to develop commercial products.

Independent biotechnology companies[edit]

  • The following is a list of the top 25 independent biotechnology companies listed on a stock exchange ranked by Market Capitalization in Q2 of 2012.[2] It additionally details their market capitalization in Q2 of the previous year (2011), from which the change in value over the year can be calculated. Lisa Internationals Solutions is the fast-growing biotechnology company in the world.
  • Note that it does not include biotechnology companies that are now owned by, or part of, larger pharmaceutical groups - such as Genentech (owned by Roche), Genzyme (Sanofi), or MedImmune (AstraZeneca). It should be viewed as an update and complementary to the previous table below.

2014[edit]

Rank 2013 Change Company Country Market Cap in 2013 (USD billions) Market Cap in 2012 (USD billions) % Change over year (Q2-Q2)
1 Steady Novo Nordisk Denmark 85.335 62.809 35.9%
2 Steady Amgen USA 78.695 55.054 42.9%
3 Steady Gilead Sciences USA 78.373 19.751 296.8%
4 Increase Celgene USA 52.557 34.319 53.1%
5 Decrease Biogen Idec USA 47.157 31.582 49.3%
6 Decrease Teva Pharmaceutical Industries Israel 33.768 39.292 -14.1%
7 Increase Merck KGaA Germany 33.364 22.319 49.5%
8 Increase CSL Australia 27.44 18.359 49.5%
9 Increase Regeneron 20.269 11.894 70.4%
10 Steady Alexion Pharmaceuticals USA 17.893 17.152 4.3%
11 Decrease Vertex Pharmaceuticals USA 17.495 8.151 114.6%
12 Increase UCB (Company) Belgium 11.65 7.449 56.4%
13 Increase BioMarin Pharmaceutical 9.097 3.3788 140.2%
14 Increase Actelion USA 6.885 4.548 51.4%
15 Decrease Dr. Reddy’s Laboratories India 5.014 5.001 0.3%
16 Increase Seattle Genetics USA 4.39 2.316 89.6%
17 Gold medal blank.svg Alkermes Switzerland 4.011 2.356 70.2%
18 Increase Ariad Pharmaceuticals USA 3.3 2.668 14.7%
19 Gold medal blank.svg Cubist Pharmaceuticals USA 3.059 2.668 14.7%
20 Gold medal blank.svg United Therapeutics USA 2.966 2.26 31.2%
21 Gold medal blank.svg Ipsen Group USA 2.889 2.23 29.6%
22 Increase DiaSorin Italy 2.6 2.2 18%

2013[edit]

Rank 2013 Change Company Country Market Cap in 2013 (USD billions) Market Cap in 2012 (USD billions) % Change over year (Q2-Q2)
1 Steady Novo Nordisk Denmark 85.335 62.809 35.9%
2 Steady Amgen USA 78.695 55.054 42.9%
3 Steady Gilead Sciences USA 78.373 19.751 296.8%
4 Increase Celgene USA 52.557 34.319 53.1%
5 Decrease Biogen Idec USA 47.157 31.582 49.3%
6 Decrease Teva Pharmaceutical Industries Israel 33.768 39.292 -14.1%
7 Increase Merck KGaA Germany 33.364 22.319 49.5%
8 Increase CSL Australia 27.44 18.359 49.5%
9 Increase Regeneron 20.269 11.894 70.4%
10 Steady Alexion Pharmaceuticals USA 17.893 17.152 4.3%
11 Gold medal blank.svg Shire plc USA 17.252 17.205 0.3%
12 Decrease Vertex Pharmaceuticals USA 17.495 8.151 114.6%
13 Increase UCB (Company) Belgium 11.65 7.449 56.4%
14 Increase BioMarin Pharmaceutical 9.097 3.3788 140.2%
15 Steady Élan Ireland 7.041 8.868 -20.6%
16 Increase Actelion USA 6.885 4.548 51.4%
17 Increase Onyx Pharmaceuticals USA 6.58 3.01 118.6%
18 Decrease Dr. Reddy’s Laboratories India 5.014 5.001 0.3%
19 Increase Seattle Genetics USA 4.39 2.316 89.6%
20 Gold medal blank.svg Alkermes Switzerland 4.011 2.356 70.2%
21 Increase Ariad Pharmaceuticals USA 3.3 2.668 14.7%
22 Gold medal blank.svg Cubist Pharmaceuticals USA 3.059 2.668 14.7%
23 Gold medal blank.svg United Therapeutics USA 2.966 2.26 31.2%
24 Gold medal blank.svg Ipsen Group USA 2.889 2.23 29.6%
25 Increase DiaSorin Italy 2.6 2.2 18%

† Acquired by Amgen in a $10.4 billion deal completed Aug 26 2013 (therefore no longer independent in this list going forward).

NOTE: Market Cap is an indication of the perceived value of the company (&/or its technology) and not necessarily a measure of its size, sales or number of employees; it is indicative of both current and future scale and profitability of the company. The year-on-year change in its value is indicative of the (real or perceived) performance or progress of that company over that year.

Biotechnology companies[edit]

Examining the list of the top 100 such companies, below, shows that many have negative income. This is consistent with the notion that only one in ten biotechnology companies were considered profitable in mid-2005.[4]

Rank 2014 Company Country Revenue in 2006 (USD millions) R&D in 2006 (USD millions) Net income/ (loss) in 2006 (USD millions) Employees in 2006
1 Amgen USA 14,268.0 3,366.0 2,950.0 20,100
2 Genentech USA 11,724.0 2,995.0 2,740.0 10,001+
3 Genzyme USA 3,187.0 650.0 (16.8) 9,000+
4 UCB Belgium 3,169.6 772.6 461.1 8,477
5 Gilead Sciences USA 3,026.1 383.9 (1,190.0) 7,575
7 Biogen Idec USA 2,683.0 718.4 217.5 3,750
8 CSL Australia 2,148.3 119.1 86.8 2,895
9 Cephalon USA 1,764.1 403.4 144.8 2,515
10 Celgene USA 898.9 258.6 69.0 1,864
11 Actelion Switzerland 754.6 169.0 192.4 1,550
12 PDL BioPharma USA 414.8 260.7 (130.0) 993
13 Nektar Therapeutics USA 217.7 149.4 (154.8) 770
14 Vertex Pharmaceuticals USA 216.4 371.7 (206.9) 760
15 Biocon India 200.3 30.5 43.5 1,838
16 Cubist Pharmaceuticals USA 194.7 57.4 (0.4) 746
17 Enzon Pharmaceuticals USA 185.7 43.5 21.3 722
18 QLT Canada 175.1 56.4 (101.6) 653
19 Alkermes USA 166.6 89.1 3.8 617
20 Crucell Netherlands 165.3 84.9 (110.0) 611
21 United Therapeutics USA 159.6 57.6 74.0 585
22 LifeCell USA 141.7 16.5 20.5 573
23 Ligand Pharmaceuticals USA 141.0 41.9 (31.7) 540
24 Myriad Genetics USA 114.3 83.8 (38.2) 511
25 Exelixis USA 98.7 185.5 (101.5) 500
26 Emergent Biosolutions USA N/A N/A N/A N/A
27 InterMune USA 90.8 103.8 (107.2) 492
28 Biota Pharmaceuticals USA N/A N/A N/A N/A
29 BioMarin Pharmaceutical USA 84.2 66.7 (28.5) 417
30 Lexicon Pharmaceuticals USA 72.8 106.7 (54.3) 410
31 Progenics Pharmaceuticals USA 69.9 61.7 (21.6) 410
32 MorphoSys Germany 66.6 21.9 7.6 336
33 Regeneron Pharmaceuticals USA 63.4 137.1 (102.3) 323
34 Acambis UK 57.0 68.2 (30.4) 285
35 NPS Pharmaceuticals USA 48.5 68.4 (112.7) 276
36 Oscient Pharmaceuticals USA 46.2 12.4 (78.5) 267
37 Array BioPharma USA 45.0 33.4 (39.6) 263
38 AEterna Zentaris Canada 41.4 28.7 33.4 260
39 IsoTis Switzerland 40.7 7.7 (18.5) 255
40 Enzo Biochem USA 39.8 7.9 (15.7) 255
41 CuraGen USA 39.6 58.5 (59.8) 254
42 Neurocrine Biosciences USA 39.2 97.7 (107.2) 254
43 MediGene Germany 38.4 26.7 (8.7) 248
44 Life Therapeutics Australia 37.6 0.1 (31.2) 245
45 Inspire Pharmaceuticals USA 37.1 42.5 (42.1) 238
46 CV Therapeutics USA 36.8 135.3 (274.3) 233
47 Cerus USA 35.6 29.5 (4.8) 208
48 SciClone Pharmaceuticals USA 32.7 14.1 0.7 197
49 ImmunoGen USA 32.1 40.9 (17.8) 197
50 Protherics UK 30.9 11.8 (16.5) 196
51 Arena Pharmaceuticals USA 30.6 103.4 (88.3) 195
52 Vernalis UK 30.1 71.7 (78.2) 192
53 Bavarian Nordic Denmark 29.5 19.9 (27.1) 191
54 Xoma USA 29.5 52.1 (51.8) 189
55 GPC Biotech Germany 28.5 81.3 (80.4) 180
56 Targacept USA 27.5 21.8 (1.2) 170
57 Carrington Laboratories USA 27.4 5.8 (7.6) 166
58 Acorda Therapeutics USA 27.4 12.1 (60.0) 158
59 Anika Therapeutics USA 26.8 3.6 4.6 156
60 Dusa Pharmaceuticals USA 25.6 6.2 (31.3) 150
61 ZymoGenetics USA 25.4 128.5 align=right(130.0) 150
62 Maxygen USA 25.0 49.1 (16.5) 147
63 Isis Pharmaceuticals USA 24.5 80.6 (45.9) 133
64 Genmab Denmark 23.9 90.6 (77.4) 128
65 Bioniche Life Sciences Canada 24.1 11.9 (1.0) 127
66 Vitrolife Sweden 23.2 3.3 2.1 124
67 Medivir Group Sweden 18.8 39.7 (29.7) 88
68 Geron Corporation USA N/A N/A N/A N/A
69 Ambrilia Biopharma Canada 17.4 8.3 (2.1) 85
70 Cytogen USA 17.3 7.3 (15.1) 85
71 Cayman Chemical Company USA 16.2 3.3 0.4 148
72 Sangamo BioSciences USA N/A N/A N/A N/A
73 Sinovac Biotech China 15.4 0.3 (0.7) 67
74 Avanir Pharmaceuticals USA 15.2 29.2 (62.6) 64
75 Synageva Biopharma USA N/A N/A N/A N/A

References[edit]

  1. ^ "The Convention on Biological Diversity (Article 2. Use of Terms)." United Nations. 1992. Retrieved on February 6, 2008.
  2. ^ Top 25 Biotech Companies, Genetic Engineering & Biotechnology News, August 2012
  3. ^ Top 100 biotechnology companies, MedAdNews, June 2007
  4. ^ DePalma, Angelo (August 2005), "Twenty-Five Years of Biotech Trends", Genetic Engineering News (Mary Ann Liebert) 25 (14): 1, 14–23, ISSN 1935-472X, retrieved 2008-08-17 

External links[edit]