This is a list of fictional universes in film and television, in which multiple works have occurred outside a single series or within a series across multiple media, either in an unnamed universe, a hypothetical future universe or in a fictional locale in our current present or past, while excluding any number of works that could reasonably be assumed to exist within the current understanding of our own universe or exist solely in a single series and medium.
||James Cameron's fictional setting in which humans seek to mine unobtanium on the fictional exoplanetary moon, Pandora. The Earth-like moon is inhabited by a sapient indigenous humanoid species called the Na'vi, and varied fauna and flora.
|Babylon 5 universe
||Future interstellar setting of the science fiction series Babylon 5, created by J. Michael Straczynski
||Buffy the Vampire Slayer
||A place in which supernatural phenomena exist, and supernatural evil can be challenged by people willing to fight against such forces and the setting of Buffy the Vampire Slayer and Angel series are set.
||Mysically tinged world set in the United States during the Dust Bowl.
||Universe created for the television series Fringe by J. J. Abrams, in which events cross between parallel universes
||Universe created for the television series Heroes by Tim Kring, in which certain people have superhuman powers
||Universe revolving around an uncharted Pacific island with mystical powers. Created by J. J. Abrams.
|Marvel Cinematic Universe
||The setting of superhero films independently developed by Marvel Studios, based on characters published in Marvel Comics.
|Matrix movie universe
||Consisting of "our world in 2199" and a false reality created by machines.
|Pirates of the Caribbean universe
||Pirates of the Caribbean: The Curse of the Black Pearl
||A fictional universe setting around the 18th century during the Golden Age of Piracy, but with various supernatural legends having existed. Based on the Disneyland attraction.
||Intergalactic setting of the Stargate film and television franchise, in which aliens play the role of ancient gods.
|Star Trek universe
||Star Trek: The Original Series
||Setting for Star Trek: The Animated Series, six feature films and four more television series.
|Star Wars Expanded Universe
||Star Wars Episode IV: A New Hope
||Encompasses all of the officially licensed, fictional background of the Star Wars universe.
|Tommy Westphall Universe
||A Hypothetical Universe that encompasses St. Elsewhere and numerous other television shows (primarily those produced by US network NBC) which are directly or indirectly connected through fictional crossovers and spin-offs.
||Main setting of Clerks, Jay and Silent Bob Strike Back, Chasing Amy, Dogma, and other Kevin Smith films.
||Main setting of Doctor Who, Torchwood, Sarah Jane and other spin-offs of the Doctor Who series.
||World in which aliens conspire with a human cabal to colonise Earth. Comprises The TV series The X-Files, its subsequent films and its two spinoffs, The Lone Gunmen and Millennium.