Furry role-playing games are role-playing games that prominently feature anthropomorphic animal characters and consequently are popular within furry fandom. This does not include all games that feature shapeshifting or animals in some fashion.
Furry Pirates by Atlas Games, and its companion game Furry Outlaws. Furry characters live in their own version of the real world circa the 15th century.
Bunnies & Burrows: inspired by popular novel Watership Down, this early, ground-breaking RPG featured realistic intelligent animal player characters with skills such as "Bun Fu". Later re-released as a GURPS conversion.
After The Bomb and its supplements, by Palladium Books in which players take on the roles of mutant animal characters in a post-apocalyptic setting. AtB was originally release as a supplement to Palladium's TMNT & Other Strangeness RPG but has since been release as its own game setting which seems to be more inspired by the surge in real life genetic science trends than mutations caused by the fallout of nuclear war.
Justifiers by StarChilde Publications: a roleplaying game in a futuristic setting where players are Beta, a genetically engineered race of anthropomorphic animals created by human corporations. The game was published in 1988.
Hakobune By Tim Peare a D20-based furry setting with high fantasy and steam punk technology
Kevin and Kell Role-Playing Game A RPG based on Bill Holbrook's Kevin and Kell webcomic. It was published in 2005 by ComStar Media.
"The Requiem" IRC-based roleplay set in an Modern-day Earth-like environment, using Humans and Anthropomorphics (furries). Active once again.
Other Suns by Niall C. Shapero, a D100 skill based Science Fiction RPG, published in 1983 by Fantasy Games Unlimited.
"World of Feila" forum-based medieval furry role play with free-form characterization and multiple storylines. Has a section that is open to all time periods and settings.
Historia Rodentia by On The Lamb Games, a supplement for the Legend Roleplaying game released by Mongoose Publishing. Taking the setting from the Brushfire Skirmish Game, a historical parody and satire of the Napoleonic Era that uses animals in the place of history's greatest armies.
Furcadia, one of the first MMOGs, lacking the proper requirements to be classified as an MMORPG.
IMVU is an instant messenger program in which you may randomly find partners to chat with, you may dress up your 3D avatar to be a furry.
Second Life has a quite large community of furries and handfuls of privately owned furry-themed areas, due in part to the wide range of avatar customizations available.
Earth Eternal is a 3-D browser based MMO that has many varieties of races and almost complete character customization. Currently offline due to the bankruptcy of its publisher. The game however, is for sale. Note, A fan run server has been created called Planet Forever. For more information go to http://planetforevergame.com
The Endless Forest is a "social screensaver" where players roam a forest as deer with human faces.
Wolfhome is a social mmo where players can walk around as wolves, fennec foxes, jackals, or coyotes, perform canine related gestures and emoticons, and chat with friends.
Spirit Tales is an mmo where your character can take on different animal classes such as ram, fox, mouse, etc. Spirit Tales is currently in closed beta.