List of neuroscience databases

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A number of online neuroscience databases are available which provide information regarding gene expression, neurons, macroscopic brain structure, and neurological or psychiatric disorders. While some databases contain descriptive and numerical data, others include postmortem brain sections or 3D MRI and fMRI images.

A list that is regularly updated can be found at the Neuroscience Information Framework database list, which contains over 2500 databases relevant to neuroscience.

Name and External Link Description Organism Level (gene, neuron, macroscopic) Data (MRI, fMRI, images, descriptive, numerical) Disorder Register to view data? Ref
Allen Brain Atlas [1] Atlas, stained sections from brains showing development and gene expression Mouse, Human Macroscopic, Gene Images Healthy No [1]
Alzheimer's Disease Neuroimaging Initiative (ADNI) [2] Structural MRI images Human Macroscopic MRI datasets Healthy and Alzheimer's Disease Yes [2]
Bipolar Disorder Neuroimaging Database [3] Meta-analysis and database of MRI studies Human Macroscopic Descriptive, numerical Bipolar Disorder No [3]
Brain Architecture Management System [4] [5] Online resource for information about neural circuitry Rat, Mouse, Human Multilevel: brain regions, connections, neurons, gene expression patterns Descriptive, numerical healthy No [6] Structural MRI images and Atlases Human Macroscopic MRI datasets Fetuses, healthy and prematurely born neonates No [4]
Braininfo [7] Atlas, schematic atlas of Macaca fascicularis Macaque Macroscopic Schematic images Healthy Yes
Brain Machine Interface Platform [8] Different types of data related to brain machine interface Human, Monkey Macroscopic, Neuron Images, Numerical Healthy No [9] fMRI coordinate database Human Macroscopic Descriptive Healthy Yes [5]
BrainMaps [10] Atlas, high resolution stained sections from brains Human, primate and non-primate (14 species in all) Neuron and Macroscopic Images Healthy No [6]
Brede Database [11] fMRI and PET coordinate database Human Macroscopic Descriptive Healthy No [7] / MSU Brain Biodiversity Bank [12] [13] Atlas, stained sections from brains and MRI images Human and 62 other species Macroscopic Images Healthy No
Cerebellar Development Transcriptome Database [14] Atlas, stained sections from mouse brains showing cerebellar development and gene expression Mouse Macroscopic, Gene Images Healthy No [8]
Collaborative Research in Computational Neuroscience [15] Many kinds of neuroscience results that are relevant for modeling Human and several other species Multiscale Spike trains, LFP, MUA, MRI Healthy Yes
Database for Reaching Experiments And Models (DREAM) [16] Reaching data. (Behavioral, generalization, adaptation, learning, spike, fMRI, uncertainty) Human and monkey Macroscopic Kinematic, Spike, fMRI Healthy Yes
The fMRI Data Center [17] fMRI datasets from published studies Human Macroscopic fMRI datasets Healthy Yes [9]
Invertebrate Brain Platform [18] Photos of dissections of invertebrates nervous systems Invertebrates (47 species in all) Macroscopic Photos Healthy No
Major Depressive Disorder Neuroimaging Database [19] Meta-analysis and database of MRI studies Human Macroscopic Descriptive, numerical Major Depressive Disorder No [10]
Mouse Brain Library [20] Atlas, stained sections from mouse brains Mouse Macroscopic Images Healthy No [11] [21] 3D models of real neurons Human, Rat, Mouse, Monkey, others Neuron Images and 3D data Healthy No [12]
NeuronDB [22] Database of Neuron properties and classification Human Neuron Descriptive Healthy No [13]
Neuroscience Information Framework [23] actually a meta database of neuroscience-relevant data incorporating over 100 databases like brainmaps, BREDE, ABA, MGI etc. Human, Mouse, Rat, Worm Microscopic, Macroscopic Datasets Healthy and Diseased No [14]
Open Access Series of Imaging Studies (OASIS) [24] Structural MRI images Human Macroscopic MRI datasets Healthy and Alzheimer's Disease Yes [15]
OpenFMRI Project [25] Functional and structural MRI datasets Human Macroscopic MRI datasets Healthy No [16]
UNC-Wisconsin Neurodevelopment Rhesus MRI Database [26] Structural and Diffusion Weighted MRI images in Native and Atlas Space Macaque Macroscopic MRI datasets Healthy No
Whole Brain Atlas [27] Atlas, Structural MRI images and PET images Human Macroscopic Images Healthy and various diseases No

Other databases[edit]

See also[edit]

External links[edit]


  1. ^ Lein, Ed S.; et al. (2007). "Genome-wide atlas of gene expression in the adult mouse brain". Nature 445 (7124): 168–176. doi:10.1038/nature05453. PMID 17151600. 
  2. ^ Jack, CR, Bernstein, MA, Fox, NC, Thompson, P, Alexander, G, Harvey, D, Borowski, B, Britson, PJ et al. (2008). "The Alzheimer's disease neuroimaging initiative (ADNI): MRI methods". Journal of Magnetic Resonance Imaging 27 (4): 685–691. doi:10.1002/jmri.21049. PMC 2544629. PMID 18302232. 
  3. ^ Kempton, M.J.; Geddes, J.R; Ettinger, U.; Williams, SC; Grasby, PM (2008). "Meta-analysis, Database, and Meta-regression of 98 Structural Imaging Studies in Bipolar Disorder". Archives of General Psychiatry 65 (9): 1017–1032. doi:10.1001/archpsyc.65.9.1017. PMID 18762588. 
  4. ^ Serag, A.; Aljabar, P.; Ball, G.; Counsell, S.J.; Boardman, J.P.; Rutherford, M.A.; Edwards, A.D.; Hajnal, J.V.; Rueckert, D. (2012). "Construction of a consistent high-definition spatio-temporal atlas of the developing brain using adaptive kernel regression". NeuroImage 59 (3): 2255–2265. doi:10.1016/j.neuroimage.2011.09.062. PMID 21985910. 
  5. ^ Laird, AR, Lancaster, JL, Fox, PT. (2005). "BrainMap: The social evolution of a functional neuroimaging database" (PDF). Neuroinformatics 3 (1): 65–78. doi:10.1385/ni:3:1:065. PMID 15897617. 
  6. ^ Mikula, S; Trotts I; Stone JM; Jones EG (2007). "Internet-enabled high-resolution brain mapping and virtual microscopy". NeuroImage 35 (1): 9–15. doi:10.1016/j.neuroimage.2006.11.053. PMC 1890021. PMID 17229579. 
  7. ^ Nielsen, F.A. (2003). The Brede database: a small database for functional neuroimaging NeuroImage 19(2), Presented at the 9th International Conference on Functional Mapping of the Human Brain, June 19--22, 2003, New York, NY.
  8. ^ Sato, A, Sekine, Y, Saruta, C, Nishibe, H, Morita, N, Sato, Y, Sadakata, T, Shinoda, Y et al. (2008). "Cerebellar development transcriptome database (CDT-DB): profiling of spatio-temporal gene expression during the postnatal development of mouse cerebellum". Neural Networks 21 (8): 1056–69. doi:10.1016/j.neunet.2008.05.004. PMID 18603407. 
  9. ^ Van Horn JD, Grethe JS, Kostelec P, Woodward JB, Aslam JA, Rus D, Rockmore D, Gazzaniga MS (2001) The Functional Magnetic Resonance Imaging Data Center (fMRIDC): the challenges and rewards of large-scale databasing of neuroimaging studiesPhilos Trans R Soc Lond B Biol Sci Aug 29;356(1412):1323-39
  10. ^ Kempton MJ, Salvador Z, Munafò MR, Geddes JR, Simmons A, Frangou S, Williams SC.; Salvador; Munafò; Geddes; Simmons; Frangou; Williams (2011). "Structural Neuroimaging Studies in Major Depressive Disorder: Meta-analysis and Comparison With Bipolar Disorder". Arch Gen Psychiatry 68 (7): 675–90. doi:10.1001/archgenpsychiatry.2011.60. PMID 21727252.  see also MRI database at
  11. ^ Rosen GD, Williams AG, Capra JA, Connolly MT, Cruz B, Lu L, Airey DC, Kulkarni K, Williams RW (2000) The Mouse Brain Library @ Int Mouse Genome Conference 14: 166.
  12. ^ Ascoli GA, Donohue DE, Halavi M. (2007). NeuroMorpho.Org: a central resource for neuronal morphologiesJ Neurosci., 27(35):9247-51 .
  13. ^ Mirsky JS, Nadkarni PM, Healy MD, Miller PL, Shepherd GM (1998) "Database tools for integrating and searching membrane property data correlated with neuronal morphology, J Neurosci Methods. 1 July 1998;82(1):105-21.
  14. ^ Gardner D, Akil H, Ascoli GA, Bowden DM, Bug W, Donohue DE, Goldberg DH, Grafstein B, Grethe JS; Akil; Ascoli; Bowden; Bug; Donohue; Goldberg; Grafstein; Grethe; Gupta; Halavi; Kennedy; Marenco; Martone; Miller; Müller; Robert; Shepherd; Sternberg; Van Essen; Williams (September 2008). "The neuroscience information framework: a data and knowledge environment for neuroscience". Neuroinformatics 6 (3): 149–60. doi:10.1007/s12021-008-9024-z. PMC 2661130. PMID 18946742. 
  15. ^ Marcus, DS, Wang, TH, Parker, J, Csernansky, JG, Morris, JC, Buckner, RL (Sep 2007). "Open Access Series of Imaging Studies (OASIS): cross-sectional MRI data in young, middle aged, nondemented, and demented older adults". J Cogn Neurosci 19 (9): 1498–507. doi:10.1162/jocn.2007.19.9.1498. PMID 17714011. 
  16. ^ Poldrack, RA, Barch, DM, Mitchell, JP, Wager, TD, Wagner, AD, Devlin, JT, Cumba, C, Koyejo, O, Milham, MP (Jul 2013). "Toward open sharing of task-based fMRI data: the OpenfMRI project". Frontiers in Neuroinformatics 7 (12): 12. doi:10.3389/fninf.2013.00012. PMC 3703526. PMID 23847528.