Littoral cell angioma

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Littoral cell angioma
Classification and external resources
Littoral cell angioma of the spleen - low mag.jpg
Low magnification micrograph of a littoral cell angioma. H&E stain.

Littoral cell angioma, abbreviated LCA, and formally known as littoral cell angioma of the spleen, is a benign tumour of the spleen that arises the from the cells that line the red pulp.[1]


LCAs can manifest with splenomegaly, persistent fever and weight loss.[2]


Littoral cell angiomas are diagnosed by pathologists. Histologically, they have anastoming small vascular channels and cystic spaces with papillary projections.[2]


The treatment for a littoral cell angioma is a splenectomy.

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  1. ^ Tan, YM.; Chuah, KL.; Wong, WK. (Jul 2004). "Littoral cell angioma of the spleen.". Ann Acad Med Singapore 33 (4): 524–6. PMID 15329769. 
  2. ^ a b Dascalescu, CM.; Wendum, D.; Gorin, NC. (Sep 2001). "Littoral-cell angioma as a cause of splenomegaly.". N Engl J Med 345 (10): 772–3. doi:10.1056/NEJM200109063451016. PMID 11547761. 

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