He was awarded Ph.D. by the State University of Utrecht in 1950 in recognition to his contributions of critically editing the Gavamayana portion of the Vedic work Jaiminiya Brahmana with the help of newly discovered manuscripts. In the Netherlands, he also studied with the famous Indologist Jan Gonda.
Lokesh Chandra knows several languages including Hindi, Sanskrit, Pali, Avesta, Old Persian, Japanese, Chinese, Tibetan, Mongolian, Indonesian, Greek, Latin, German, French, and Russian.
He has to his credit over 360 works and text editions. Among them are classics like his Tibetan-Sanskrit Dictionary, Materials for a History of Tibetan Literature, Buddhist Iconography of Tibet, and his Dictionary of Buddhist Art in about 20 volumes.