The Evil Dr. Frankenbeans has built robots of extraordinary power. Dr. Frankenbeans is ready to try to destroy the Looney Tunes and he will stop at nothing! His plan is to destroy the Looney Tunes' past, causing them to not exist in the present! It is time for the Looney Tunes to fight back! Arm your Tune with looney super weapons and suits. Get ready to fight back and go through a looney adventure. So the question is; are you ready to fight back or not?
The story begins with Bugs falling from the sky and flying right past Dr. Frankenbeans' lair which originally said "Evil Scientist Boo!" but was changed to "Evil Scientist Bo!". He then says "I knew I should've made a left at Albuquerque." The Robots see him and after Marvin is slingshot to the castle, the player begins the game. During Gameplay, (s)he will find blueprints of bosses which he will defeat. After the first boss, they Marvin and Bugs rocket to Mars to meet the other members of the organization where they use the time machine plans to stop the Doctor.
The game features both single player and two-player cooperative play. Gameplay is similar to many platformer games including combat, puzzle solving and vehicle-based levels. The game also features an "Acme Battle Mode". In this mode, two players fight each other as different characters.
The STOP and GO signs directing traffic in Drip-Along Daffy direct the train traffic in the Wild West level. Also, the environment in that cartoon is also included in the Wild West level. Nasty Canasta, the antagonist of that short, appears as an enemy in several levels.