Loracarbef

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Loracarbef
Loracarbef.png
Systematic (IUPAC) name
(6R,7S)-7-[[(2S)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Clinical data
Trade names Lorabid
AHFS/Drugs.com monograph
MedlinePlus a601206
Legal status ?
Pharmacokinetic data
Protein binding 25%
Identifiers
CAS number 76470-66-1 YesY
ATC code J01DC08
PubChem CID 5284584
DrugBank DB00447
ChemSpider 4447634 YesY
UNII W72I5ZT78Z N
KEGG D08143 YesY
ChEMBL CHEMBL1013 N
Chemical data
Formula C16H16ClN3O4 
Mol. mass 349.769 g/mol
 N (what is this?)  (verify)

Loracarbef is an antibiotic.[1] Its use was discontinued in 2006.[citation needed] It is a carbacephem, but it is sometimes grouped together with the second-generation cephalosporin antibiotics. It was marketed under the trade name Lorabid. Loracarbef is a synthetic "carba" analogue of cefaclor, and is more stable chemically. Diarrhea is the most common adverse effect with Loracarbef. Side effects are more frequently seen with children under the age of twelve. It received FDA approval in 1991.

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