Loracarbef

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Loracarbef
Loracarbef.png
Systematic (IUPAC) name
(6R,7S)-7-[[(2S)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Clinical data
Trade names Lorabid
AHFS/Drugs.com monograph
MedlinePlus a601206
Legal status
?
Pharmacokinetic data
Protein binding 25%
Identifiers
CAS number 76470-66-1 YesY
ATC code J01DC08
PubChem CID 5284584
DrugBank DB00447
ChemSpider 4447634 YesY
UNII W72I5ZT78Z N
KEGG D08143 YesY
ChEMBL CHEMBL1013 N
Chemical data
Formula C16H16ClN3O4 
Mol. mass 349.769 g/mol
 N (what is this?)  (verify)

Loracarbef is an antibiotic.[1] It is a carbacephem, but it is sometimes grouped together with the second-generation cephalosporin antibiotics. Loracarbef is a synthetic "carba" analog of cefaclor, and is more stable chemically.

History[edit]

Loracarbef received FDA approval in 1991 and it was marketed under the trade name Lorabid. Its use was discontinued in 2006.[citation needed]

Side effects[edit]

Diarrhea is the most common adverse effect with loracarbef. Side effects are more frequently seen with children under the age of twelve.

References[edit]

External links[edit]