His parents were François Godin and Elisabeth Charron. He was graduated at the College of Louis le Grand, and studied astronomy under Joseph-Nicolas Delisle. His astronomical tables (1724) gave him reputation, and the French Academy of Sciences elected him a pensionary member. He was commissioned to write a continuation of the history of the academy, left uncompleted by Bernard le Bovier de Fontenelle, and was also authorized to submit to the minister, Cardinal André-Hercule de Fleury, the best means of discovering the truth in regard to the figure of the earth, and proposed sending expeditions to the equator and the polar sea. The minister approved the plan and appropriated the necessary means, the academy designating Charles Marie de La Condamine, Pierre Bouguer, and Godin to go to Peru in 1734.
The expedition sailed from Rochelle, May 16, 1735, touched at Cadiz to take two naval lieutenants, whom Philip V had ordered to accompany it, and proceeded to Santo Domingo, where they remained six months to take observations. They arrived in Quito in February 1736, immediately crossed the Andes to establish their stations in the interior, and remained two years.
When they had finished their task in 1738, at the invitation of the Viceroy of Peru, Godin accepted the professorship in mathematics in Lima, where he also established a course of astronomical lectures. When in 1746 an earthquake destroyed the greater part of Lima, he took valuable seismological observations, assisted the sufferers, and made plans by the use of which the new buildings would be less exposed to danger from renewed shocks.
In 1751 he returned to Europe, but found that he had been nearly forgotten, and superseded as pensioner of the academy; and, as his fortune had been lost in unfortunate speculations, he accepted the presidency of the college for midshipmen in Cadiz in 1752. During the earthquake of Lisbon, 1755, which was distinctly felt at Cadiz, he took observations and did much to allay the apprehensions of the public, for which he was ennobled by the king of Spain. In 1759 he was called to Paris and reinstated as pensionary member of the academy, but he died on his return to Cadiz.
- Appendix aux tables astronomiques de Lahire (Paris, 1724)
- Histoire de l'académie des sciences, 1680 à '99 (11 vols., 1728)
- La connaissance des temps (1730–1733)
- El temblor de tierra de Lima, sus causas, efectos y consecuencias (Lima, 1748)
- Curso de matemáticas para el uso de mis discípulos (1750)
- Observations astronomiques au Perou (2 vols., Paris, 1752)
- Des tremblements de terre en général, de ceux de Lima et Lisbonne en particulier (1753)
- Les possessions Espagnoles dans l'Amérique du Sud; le Perou, son histoire, ses richesses, et moeurs de ses habitants (1755).
- Ferreiro, Larrie (2011). Measure of the Earth: The Enlightenment Expedition that Reshaped Our World. New York: Basic Books. p. 376. ISBN 978-0-465-01723-2.
- Wilson, James Grant; Fiske, John, eds. (1900). "Godin, Louis". Appletons' Cyclopædia of American Biography. New York: D. Appleton.