Louisville Defender is a weekly newspaper in Louisville, Kentucky. It was founded in 1933 by Alvin Bowman of Louisville and John Sengstacke of Chicago. It joined The Louisville Leader and Louisville News as African-American newspapers in the city. Frank Stanley Sr. bought Sengstacke's share in 1936, and published the paper for the next 37 years.
Stanley's column, "Being Frank", became nationally syndicated in the 1940s. After his death, his wife and sons became co-publishers, and the family eventually sold its ownership in 1985.