Because Mobile and Baldwin Counties tend to use South Alabama with exclusivity, a second use of "Lower Alabama" is to refer to the other parts of southern Alabama, including the Florida-border counties from Escambia County over to Houston County. Traditionally, the south central and southeastern parts of the state are representative of an older era in Alabama. Hence, Lower Alabama, suggests that this region is less wealthy than other parts of the state. These sections of the state are where jokes are often heard with punch lines of "Yep, I'm from L.A. too: Lower Alabama"; or references to natives of southeastern Alabama being "Born in East L.A." (better known as the title of a Cheech Marinsong parody of Bruce Springsteen's Born in the U.S.A.). Further evidence of this region's claim was the "University of Lower Alabama" as one of the considered name changes by Troy State University before it became Troy University.
Some people in North Alabama refer to Lower Alabama as anywhere below the Cherokee Nation line in Marshall County or any other Upper Alabama county whose water drains to the Tennessee River instead of through the Alabama River watershed.
Lower Alabama is also a pejorative slang term used by some Floridians to refer to the part of Florida directly south of Alabama, especially the area around Pensacola, and eastward to Destin and Panama City. This is often jokingly shortened to "L.A.", though this term is also used extensively by Alabamians too.