Lucanthone
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| This article does not cite any references or sources. (November 2012) |
| Systematic (IUPAC) name | |
|---|---|
| 1-{[2-(diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 479-50-5 |
| ATC code | None |
| PubChem | CID 10180 |
| DrugBank | DB04967 |
| ChemSpider | 9772 |
| UNII | FC6D57000M |
| ChEBI | CHEBI:51052 |
| Chemical data | |
| Formula | C20H24N2OS |
| Mol. mass | 340.48 g/mol |
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Lucanthone is a drug used in chemotherapy. It is a prodrug and is converted to an active metabolite "hycanthone".
Mechanism of action [edit]
Hycanthone binds to acetylcholine receptors in the worm and results in increased sensitivity to stimulation by 5-HT causing increase in motility, paired worms are separated and reproduction is stopped. It cause damage of the integument and vitelline duct.
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