Ludwig Institute for Cancer Research
Ludwig Cancer Research is an international community of scientists dedicated to preventing and controlling cancer. It encompasses the Ludwig Institute for Cancer Research (LICR) and the Ludwig centers at six US institutions, all pursuing discoveries to alter the course of cancer. It was endowed with substantially all of philanthropist Daniel K. Ludwig's international and domestic holdings, amounting to US$2.5 billion committed to cancer research to date.
Research areas of focus include: cell biology, clinical trials, genomics, immunology, neuroscience, prevention, signalling, stem cells, therapeutics and tumor biology.
Daniel K. Ludwig was a shipping magnate who parleyed a $5,000 loan from his father into a global business empire based on a fleet of supertankers. In the 1960s and 1970s, he was among the richest men in the world, with a self-made empire of some 200 companies spread around the world. He left substantially all of his fortune to cancer research, believing that cancer represented one of the great challenges of humanity.
Born in South Haven, Michigan, on June 24, 1897, Ludwig invented the modern supertanker and pioneered the development of a great supertanker fleet. He participated in major oil and gas projects throughout the world, became a major investor and operator in the production of coal and other minerals, acquired and developed luxury hotels and real estate properties, and developed a forest-products and agricultural enterprise that encompassed three million acres in the Amazon basin. He died at the age of 95 in New York on August 27, 1992.
- 1971: establishment of the Ludwig Institute for Cancer Research
- 2006: establishment of the Ludwig centers in the United States
The Ludwig Institute for Cancer Research is an international not-for-profit organization committed to improving the understanding and control of cancer. The institute conducts its own research and translates discoveries into applications for patient benefit. It fosters collaborative research and supports six scientific initiatives across basic and translational research: brain cancer, breast cancer, cancer prevention, colon cancer, immunotherapy and melanoma. The institute also has a dedicated technology development program to ensure the translation of its promising technologies. It includes teams focused on intellectual property, licensing, small molecule discovery, the conduct of clinical trials and the creation of start-up companies.
Established in 1971, the institute employs approximately 600 scientists, clinicians and support personnel worldwide. Research support is principally provided by the institute and supplemented with governmental and other grants. Since its inception, the institute has invested US$1.6 billion of its own resources in cancer research.
On January 6, 2014 it was announced that Harvard University Johns Hopkins University, the University of Chicago, and Stanford University were among six institutions sharing a $540 million grant from Ludwig Cancer Research, using funds established by Daniel K. Ludwig for research into cancer.
- Brussels branch at the de Duve Institute of the Université catholique de Louvain
- Lausanne branch at the Ludwig Centre for Cancer Research of the University of Lausanne
- Melbourne branch at the Olivia Newton-John Cancer and Wellness Centre of Austin Hospital
- Oxford branch at the Nuffield Department of Clinical Medicine of the University of Oxford
- San Diego branch at the University of California at San Diego
- Sao Paulo branch at the Molecular Oncology Center of the Hospital Sírio-Libanês
- Stockholm branch at the Karolinska Institute
- Uppsala branch at the Biomedical Center of the University of Uppsala
The Ludwig centers are dedicated cancer research laboratories at six US research institutions. Under the terms of Daniel K. Ludwig’s will, the centers were established in 2006. To date, they have received US$900 million from the Virginia and Daniel K. Ludwig Fund for Cancer Research. The centers operate independently of the Ludwig Institute, but by the terms of the grant their directors and scientists are to work collaboratively with each other and with the institute. Prior to the formation of the Ludwig centers, each academic institution was endowed with two Virginia and Daniel K. Ludwig Professorships.
- Baltimore: Ludwig Center at the Johns Hopkins University
- Boston: Ludwig Center at the Dana-Farber Cancer Institute and the Harvard University
- Boston: Ludwig Center at the Massachusetts Institute of Technology
- Chicago: Ludwig Center at the University of Chicago
- New York: Ludwig Center (and Ludwig Collaborative Laboratory) at the Memorial Sloan Kettering Cancer Center
- Palo Alto: Ludwig Center at the Stanford University
Notes and references
- Ludwig Research Areas, Ludwig Cancer Research official website (retrieved August 15, 2013)
- Pace, Eric (August 29, 1992). “Daniel Ludwig, Billionaire Businessman, Dies at 95.” The New York Times.
- Colvin, Richard Lee(August 29, 1992). “Shipping Magnate Who Created Westlake Dies” The Los Angeles Times.
- US Patent and Trademark Office (page visited on 15 August 2013).
- http://www.ClinicalTrials.gov/ (page visited on 15 August 2013).
- "Strategic Transactions", Elsevier Business Intelligence (page visited on 15 August 2013).
- "Harvard Among Six Centers Sharing $540 Million". Bloomberg. January 6, 2014.