The Luke Jillson House is an historic house at 2510 Mendon Road in Cumberland, Rhode Island. It was built around 1752 and is an excellent example of a Georgian style house of the time.
The house is two and one-half stories tall with a flank gable roof and two interior brick chimneys, reflecting a central hall plan. The entrance, centered in a five-bay facade, has fluted pilasters supporting a cushion frieze surmounted by a modillion-trimmed cornice and pediment. A four-story, square, Italianate tower, constructed in the 19th century and connecting to a long, one-story addition, is attached to the rear elevation.
The dwelling is noted primarily for its architecture, which attests to the reputed affluence and prominence of Luke Jillson, about whom little is known. It was added to the National Register of Historic Places in 1982.