Luke Montgomery helped lead efforts to distribute over 500 safer-sex packets outside Seattle high schools. In 1993, he changed his last name to "Sissyfag", in an effort to make a point about discrimination against gays and lesbians, a move that was covered in papers from USA Today to The Sydney Morning Herald. Two years later he changed his name back to Montgomery, and spoke against what he considered counterfeit and self-destructive expressions of sexual orientation.
On December 1, 1993, World AIDS Day, Montgomery attended a speech in Washington, D.C., by President Bill Clinton marking the occasion. Montgomery interrupted the speech and shouted at the president that he was not taking enough action against the disease. The protest was widely publicized and was even covered in The New York Times editorial page, and Montgomery said he had staged it to remind AIDS activists of their responsibility to hold Clinton to his campaign promises. Montgomery also protested the next year at speeches by Secretary of Health and Human Services Donna Shalala and an Easter service that Clinton attended.
Montgomery ran for mayor of Washington, D.C., unsuccessfully.
Montgomery is also an animal rights activist. He worked in Los Angeles near the end of the 1990s on the staff of the animal rights group Last Chance for Animals. He started a ballot initiative, "Beverly Hills Consumers for Informed Choices," to require all fur coats sold in Beverly Hills to carry a label describing how fur manufacturers put animals to death. The initiative did gather the necessary number of signatures to appear on the ballot, but was defeated in the election.
Montgomery's personal website defines his current activity as "a marketing and Internet fundraising consultant for non-profits and a media strategist whose work has captured front page coverage in The New York Times, The Washington Post, and The Los Angeles Times. The website also discussed his work in non-profit marketing and animal welfare. Montgomery has worked with the Humane Society of the United States and the Society for the Prevention of Cruelty to Animals of Canada, and was a founder and designer of 1-800-Save-A-Pet.com.
In September 2005, Montgomery, with Tom Kertes, started "Bill for First Lady.com", a humorous web campaign whose stated objective was to build support for a 2008 presidential run by Hillary Clinton and "to tickle the red states pink and make the Republican attack jokes old news". The website features videos of "First Lady" Bill Clinton wearing a woman's suit.
Montgomery raised funds and volunteered in Haiti with earthquake relief efforts along with his ex-partner Nate Gaudias via Cause Commandos
In 2010, Montgomery founded the online T-shirt retailer FCKH8.
In 2012, Luke and (his partner) Eduardo Cisneros (director of Silent Story), started the "Legalize Love" campaign. They then covered their Volkswagen Beetle in over 1,000 "Legalize Love" stickers in relation to President Obama's stance on same-sex marriage. They then went on a 2,400mile across states who are voting on the same-sex marriage laws (including Maryland, Maine, Minnesota and Washington).Also a short film was made for the campaign.
- "Out of Luke". The Advocate. 1995-11-14. p. 15. Retrieved 2010-07-28.
- Muzzy, Frank (2005), Gay and Lesbian Washington D.C., Charleston, SC: Arcadia Pub., p. 91, ISBN 0-7385-1753-4
- "Montgomery, campaign manager for Beverly Hills Consumers for Informed Choices", CNN, February 4, 1999, archived from the original on October 5, 2007, retrieved 2007-11-01[dead link]
- "Sissyfag strikes again". The Advocate. 1999-06-22. p. 16. Retrieved 2010-07-28.
- Jones, Susan (September 20, 2005), "Hillary-for-President Website Jokes About Bill As First Lady", CNSNews.com, retrieved 2007-11-01[dead link][dead link]
- "'Legalize Love Bug' Takes Gay Couple's Support For President Obama On The Road". www.huffingtonpost.com. 10 October 2012. Retrieved 25 January 2014.