Lynn J. Rothschild
|Lynn J. Rothschild|
May 11, 1957 |
New York, New York, United States of America
|Institutions||NASA’s Ames Research Center, Brown, Stanford, UC Santa Cruz|
|Alma mater||Yale University, Indiana University, Brown University|
|Known for||Extremophiles, Synthetic biology at NASA|
Lynn J. Rothschild (born May 11, 1957) is an evolutionary biologist, astrobiologist and synthetic biologist at NASA's Ames Research Center, and a consulting Professor at Stanford University, where she teaches Astrobiology and Space Exploration. She is also an adjunct Professor at Brown University. At Ames her research has focused on how life, particularly microbes, has evolved in the context of the physical environment, both on Earth and potentially beyond our planet's boundaries. Since 2007 she has studied the effect of UV radiation on DNA synthesis, carbon metabolism and mutation/DNA repair in the Rift Valley of Kenya and the Atacama desert of Bolivia, and also in high altitude experiments atop Mt. Everest, in balloon payloads with BioLaunch and in collaboration with Mavericks Civilian Space Foundation.
Rothschild's research focus is in two main areas: astrobiology and synthetic biology. Rothschild has studied carbon metabolism and DNA damage and repair in the laboratory setting and on algae, work that has taken her to field sites in such locations as the thermal areas in Yellowstone National Park, New Zealand, Australia, Kenya's Rift Valley, hypersaline environments in the San Francisco Bay, Baja California and the Bolivian Andes. Her current lab members are actively pursuing topics ranging from a protein-first model to algae and synthetic biology. She has taken to the air in conjunction with the Aeronautics and Astronautics Department at Stanford and Mavericks Civilian Rocket Foundation, flying experiments up to 106,000 feet (32 km) on high altitude balloons. Courtesy of the Galathea 3, she has also had experiments on a Danish oceanographic cruise from South America to Copenhagen.
Rothschild has been instrumental in developing the field of astrobiology. She founded and ran the first three Astrobiology Science Conferences (AbSciCon), was the founding co-editor of the International Journal of Astrobiology, and is the former director of the Astrobiology Strategic Analysis and Support Office for NASA. She has been a member of the Astrobiology Institute since its inception.
Rothschild has been instrumental in bringing synthetic biology to NASA. She has served as the NASA representative to the OSTP Working Group on Synthetic Biology and has been the faculty advisor to the award-winning Brown-Stanford 2011, and Stanford-Brown 2012 and 2013 iGEM teams.
Rothschild lectures frequently worldwide, including at the Vatican and Windsor Castle, Mystic Seaport and the Royal Society of London. Rothschild's lecture at the annual Molecular Frontiers Symposium at the Royal Swedish Academy of Sciences in Stockholm, May 2013, "Life in Extreme Environments and the Search for Life in the Universe" can be viewed online. She appears frequently on radio and television programs, including the BBC, NPR, National Geographic, Discovery Channel, ABC World News Tonight, and the History Channel and most recently on Morgan Freeman’s "Through the Wormhole" on the Science Channel. Rothschild is a Fellow of the Linnean Society of London, and also a Fellow of the California Academy of Sciences and the Explorers Club.
- Horikawa DD, Cumbers J, Sakakibara I, Rogoff D, Leuko S, Harnoto R, Arakawa K, Katayama T, Kunieda T, Toyoda A, Fujiyama A, Rothschild LJ (2013). "Analysis of DNA repair and protection in the Tardigrade Ramazzottius varieornatus and Hypsibius dujardini after exposure to UVC radiation.". PLoS One 8 (6): e64793. doi:10.1371/journal.pone.0064793.
- Rothschild LJ (2010). "A Powerful Toolkit for Synthetic Biology: over 3.8 billion years of evolution". BioEssays 32 (4): 304–313. doi:10.1002/bies.200900180. PMID 20349441.
- Leuko S, Rothschild LJ, Burns BP (2010). "Halophilic Archaea and the Search for Extinct and Extant Life on Mars". J. Cosomology 5: 940–50. Bibcode:2010JCos....5..940L.
- Balk M, Bose M, Ertem G, Rogoff DA, Rothschild LJ, Freund FT; Bose; Ertem; Rogoff; Rothschild; Freund (2009). "Oxidation of Water to Hydrogen Peroxide at the Rock-water Interface due to Stress-activated Electric Currents in Rocks". Earth and Planetary Letters 283: 87–92. Bibcode:2009E&PSL.283...87B. doi:10.1016/j.epsl.2009.03.044.
- Rothschild LJ (2008). "The evolution of photosynthesis….again?". Philosophical Transactions of the Royal Society B 363 (1504): 2787–2801. doi:10.1098/rstb.2008.0056.
- D’Antoni H, Rothschild L, Schultz C, Burgess S, Skiles JW (2007). "Extreme environments in the forests of Ushuaia, Argentina". Geophys. Res. Lett. 34 (22): L.22704. Bibcode:2007GeoRL..3422704D. doi:10.1029/2007GL031096.
- Tarter JC, Backus PR, Mancinelli RL, Aurnou JM, Backman DE, Basri GS, Boss AP, Clarke A, Deming D, Doyle LR, Feigelson ED, Freund F, Grinspoon DH, Haberle RM, Hauck SA II, Heath MJ, Henry TJ, Hollingsworth JL, Joshi MM, Kilston S, Liu MC, Meikle E, Reid IN, Rothschild LJ, Scalo JM, Segura A, Tang CM, Tiedje JM, Turnbull MC, Walkowicz LM, Weber AL, Young RE; Backus; Mancinelli; Aurnou; Backman; Basri; Boss; Clarke et al. (2007). "A Re-appraisal of the Habitability of Planets Around M Dwarf Stars". Astrobiology 7 (1): 30–65. arXiv:astro-ph/0609799. Bibcode:2007AsBio...7...30T. doi:10.1089/ast.2006.0124. PMID 17407403.
- Southam G, Rothschild L, Westall F (2007). "The Geology and Habitability of Terrestrial Planets: fundamental requirements for life". Space Science Reviews 129 (1–3): 7–34. Bibcode:2007SSRv..129....7S. doi:10.1007/s11214-007-9148-8.
- Foster JS, Singh AK, Rothschild LJ, Sherman LA (2006). "Growth-Phase Dependent Differential Gene Expression in Synechocystis sp. Strain PCC 6803 and Regulation by a Group 2 Sigma Factor". Archives of Microbiology. doi:10.1007/s00203-006-0193-6.
- Rothschild LJ, Mancinelli RL (2001). "Life in Extreme Environments". Nature 409 (6823): 1092–1101. doi:10.1038/35059215. PMID 11234023.
- Bishop JL, Louris SK, Rogoff DA, Rothschild LJ (2006). "Iron Oxide: an Early Sunscreen for Photosynthetic Microbes?". Internatl. J. Astrobiology 5: 1–12. Bibcode:2006IJAsB...5....1B. doi:10.1017/S1473550406002886.
- Rothschild LJ, Lister A, ed. (2003). "Evolution on Planet Earth: The Impact of the Physical Environment". Academic Press. p. 456. ISBN 0-125-98655-6.
- Profile for Solar System Exploration
- Astrobiology and Space Exploration
- Profile at Brown
- Course Lectures Winter 2010 on Stanford iTunes
- Winter 2009 lectures on Stanford Youtube
- Lecture on Life at the Edge: The Search for Life in Extreme Environments and in the Universe Part of the Silicon Valley Astronomy Lecture Series