The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway.
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Ikeda A, Sakuma H, Masaki M, Kozutsumi Y, Oka S, Inazawa J et al. (2002). "Genomic organization and fine-mapping of the human leucine zipper-bearing kinase (LZK) gene". J. Biochem. Mol. Biol. Biophys.6 (2): 113–7. doi:10.1080/10258140290027243. PMID12186766.
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