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MAP/microtubule affinity-regulating kinase 1
Protein MARK1 PDB 2hak.png
PDB rendering based on 2hak.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols MARK1 ; MARK; Par-1c; Par1c
External IDs OMIM606511 MGI2664902 HomoloGene49552 IUPHAR: 2097 ChEMBL: 5940 GeneCards: MARK1 Gene
EC number,
RNA expression pattern
PBB GE MARK1 221047 s at tn.png
More reference expression data
Species Human Mouse
Entrez 4139 226778
Ensembl ENSG00000116141 ENSMUSG00000026620
UniProt Q9P0L2 Q8VHJ5
RefSeq (mRNA) NM_001286124 NM_145515
RefSeq (protein) NP_001273053 NP_663490
Location (UCSC) Chr 1:
220.7 – 220.84 Mb
Chr 1:
184.9 – 185 Mb
PubMed search [1] [2]

Serine/threonine-protein kinase MARK1 is an enzyme that in humans is encoded by the MARK1 gene.[1][2]


  1. ^ Drewes G, Ebneth A, Preuss U, Mandelkow EM, Mandelkow E (May 1997). "MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption". Cell 89 (2): 297–308. doi:10.1016/S0092-8674(00)80208-1. PMID 9108484. 
  2. ^ "Entrez Gene: MARK1 MAP/microtubule affinity-regulating kinase 1". 

Further reading[edit]