MAS1

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MAS1 proto-oncogene, G protein-coupled receptor
Identifiers
Symbols MAS1 ; MAS; MGRA
External IDs OMIM165180 MGI96918 HomoloGene1782 IUPHAR: MAS1 GeneCards: MAS1 Gene
RNA expression pattern
PBB GE MAS1 208210 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 4142 17171
Ensembl ENSG00000130368 ENSMUSG00000068037
UniProt P04201 P30554
RefSeq (mRNA) NM_002377 NM_008552
RefSeq (protein) NP_002368 NP_032578
Location (UCSC) Chr 6:
160.33 – 160.33 Mb
Chr 17:
12.84 – 12.87 Mb
PubMed search [1] [2]

MAS proto-oncogene is a protein that in humans is encoded by the MAS1 gene.[1]

The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.[1]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.