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Matrilin 2
Symbol MATN2
External IDs OMIM602108 MGI109613 HomoloGene20538 GeneCards: MATN2 Gene
RNA expression pattern
PBB GE MATN2 202350 s at tn.png
More reference expression data
Species Human Mouse
Entrez 4147 17181
Ensembl ENSG00000132561 ENSMUSG00000022324
UniProt O00339 O08746
RefSeq (mRNA) NM_002380 NM_016762
RefSeq (protein) NP_002371 NP_058042
Location (UCSC) Chr 8:
98.88 – 99.05 Mb
Chr 15:
34.31 – 34.44 Mb
PubMed search [1] [2]

Matrilin-2 is a protein that in humans is encoded by the MATN2 gene.[1][2][3]

This gene encodes a member of the von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains five von Willebrand factor A domains. The specific function of this gene has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.[3]


  1. ^ Deak F, Piecha D, Bachrati C, Paulsson M, Kiss I (May 1997). "Primary structure and expression of matrilin-2, the closest relative of cartilage matrix protein within the von Willebrand factor type A-like module superfamily". J Biol Chem 272 (14): 9268–74. doi:10.1074/jbc.272.14.9268. PMID 9083061. 
  2. ^ Mates L, Korpos E, Deak F, Liu Z, Beier DR, Aszodi A, Kiss I (Mar 2002). "Comparative analysis of the mouse and human genes (Matn2 and MATN2) for matrilin-2, a filament-forming protein widely distributed in extracellular matrices". Matrix Biol. 21 (2): 163–74. doi:10.1016/S0945-053X(01)00194-9. PMID 11852232. 
  3. ^ a b "Entrez Gene: MATN2 matrilin 2". 

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