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MDK may refer to:



  • MDK, Inc., the manufacturing company that makes K-Line (a brand name of O gauge and S gauge model railway locomotives, rolling stock, and buildings)
  • A human gene which makes a protein called Midkine which is also known as neurite growth-promoting factor 2 (NEGF2)
  • Minedykkerkommandoen, a Norwegian clearance diver force
  • GNU MIX Development Kit (GNU MDK)
  • In software development, Module Developer Kit