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Mediator complex subunit 25
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols MED25 ; ACID1; ARC92; CMT2B2; P78; PTOV2
External IDs OMIM610197 MGI1922863 HomoloGene12614 GeneCards: MED25 Gene
RNA expression pattern
PBB GE MED25 215897 at tn.png
PBB GE MED25 208110 x at tn.png
More reference expression data
Species Human Mouse
Entrez 81857 75613
Ensembl ENSG00000104973 ENSMUSG00000002968
UniProt Q71SY5 Q8VCB2
RefSeq (mRNA) NM_030973 NM_029365
RefSeq (protein) NP_112235 NP_083641
Location (UCSC) Chr 19:
50.32 – 50.34 Mb
Chr 7:
44.88 – 44.89 Mb
PubMed search [1] [2]

Mediator of RNA polymerase II transcription subunit 25 is an enzyme that in humans is encoded by the MED25 gene.[1][2][3]


MED25 has been shown to interact with MED4.[4]


  1. ^ Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Jun 1997). "Large-scale concatenation cDNA sequencing". Genome Res 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174. 
  2. ^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166. 
  3. ^ "Entrez Gene: MED25 mediator of RNA polymerase II transcription, subunit 25 homolog (S. cerevisiae)". 
  4. ^ Tomomori-Sato, Chieri; Sato Shigeo, Parmely Tari J, Banks Charles A S, Sorokina Irina, Florens Laurence, Zybailov Boris, Washburn Michael P, Brower Christopher S, Conaway Ronald C, Conaway Joan Weliky (Feb 2004). "A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2". J. Biol. Chem. (United States) 279 (7): 5846–51. doi:10.1074/jbc.M312523200. ISSN 0021-9258. PMID 14638676. 

Further reading[edit]

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