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Matrix metallopeptidase 27
Symbols MMP27 ; MMP-27
External IDs MGI3039232 HomoloGene23345 GeneCards: MMP27 Gene
Species Human Mouse
Entrez 64066 234911
Ensembl ENSG00000137675 ENSMUSG00000070323
UniProt Q9H306 D3YV89
RefSeq (mRNA) NM_022122 NM_001030289
RefSeq (protein) NP_071405 NP_001025460
Location (UCSC) Chr 11:
102.56 – 102.58 Mb
Chr 9:
7.57 – 7.58 Mb
PubMed search [1] [2]

Matrix metallopeptidase 27 also known as MMP27 is an enzyme which in humans is encoded by the MMP27 gene.[1]


Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.[2]


  1. ^ Nagase H, Woessner JF (July 1999). "Matrix metalloproteinases". J. Biol. Chem. 274 (31): 21491–4. doi:10.1074/jbc.274.31.21491. PMID 10419448. 
  2. ^ "Entrez Gene: MMP27". 

External links[edit]

  • The MEROPS online database for peptidases and their inhibitors: M10.027

This article incorporates text from the United States National Library of Medicine, which is in the public domain.