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Mortality factor 4 like 1
Protein MORF4L1 PDB 2aql.png
PDB rendering based on 2aql.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols MORF4L1 ; Eaf3; HsT17725; MEAF3; MORFRG15; MRG15; S863-6
External IDs OMIM607303 MGI1096551 HomoloGene86043 GeneCards: MORF4L1 Gene
Species Human Mouse
Entrez 10933 21761
Ensembl ENSG00000185787 ENSMUSG00000062270
UniProt Q9UBU8 P60762
RefSeq (mRNA) NM_001265603 NM_001039147
RefSeq (protein) NP_001252532 NP_001034236
Location (UCSC) Chr 15:
79.1 – 79.19 Mb
Chr 9:
90.09 – 90.11 Mb
PubMed search [1] [2]

Mortality factor 4-like protein 1 is a protein that in humans is encoded by the MORF4L1 gene.[1][2][3]


MORF4L1 has been shown to interact with MYST1,[4] Retinoblastoma protein[4][5] and MRFAP1.[4][5]


  1. ^ Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474. 
  2. ^ Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Jun 1997). "Large-scale concatenation cDNA sequencing". Genome Res 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174. 
  3. ^ "Entrez Gene: MORF4L1 mortality factor 4 like 1". 
  4. ^ a b c Pardo, Patricia S; Leung James K, Lucchesi John C, Pereira-Smith Olivia M (Dec 2002). "MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation". J. Biol. Chem. (United States) 277 (52): 50860–6. doi:10.1074/jbc.M203839200. ISSN 0021-9258. PMID 12397079. 
  5. ^ a b Leung, J K; Berube N; Venable S; Ahmed S; Timchenko N; Pereira-Smith O M (Oct 2001). "MRG15 activates the B-myb promoter through formation of a nuclear complex with the retinoblastoma protein and the novel protein PAM14". J. Biol. Chem. (United States) 276 (42): 39171–8. doi:10.1074/jbc.M103435200. ISSN 0021-9258. PMID 11500496. 

Further reading[edit]