MPP1

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Membrane protein, palmitoylated 1, 55kDa
Protein MPP1 PDB 2ev8.png
PDB rendering based on 2ev8.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols MPP1 ; AAG12; DXS552E; EMP55; MRG1; PEMP
External IDs OMIM305360 MGI105941 HomoloGene1826 GeneCards: MPP1 Gene
RNA expression pattern
PBB GE MPP1 202974 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 4354 17524
Ensembl ENSG00000130830 ENSMUSG00000031402
UniProt Q00013 P70290
RefSeq (mRNA) NM_001166460 NM_008621
RefSeq (protein) NP_001159932 NP_032647
Location (UCSC) Chr HG1497_PATCH:
153.99 – 154.03 Mb
Chr X:
75.11 – 75.13 Mb
PubMed search [1] [2]

55 kDa erythrocyte membrane protein is a protein that in humans is encoded by the MPP1 gene.[1][2]

Palmitoylated membrane protein 1 is the prototype of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 1 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction.[2]

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