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Membrane protein, palmitoylated 1, 55kDa
Protein MPP1 PDB 2ev8.png
PDB rendering based on 2ev8.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols MPP1 ; AAG12; DXS552E; EMP55; MRG1; PEMP
External IDs OMIM305360 MGI105941 HomoloGene1826 GeneCards: MPP1 Gene
RNA expression pattern
PBB GE MPP1 202974 at tn.png
More reference expression data
Species Human Mouse
Entrez 4354 17524
Ensembl ENSG00000130830 ENSMUSG00000031402
UniProt Q00013 P70290
RefSeq (mRNA) NM_001166460 NM_008621
RefSeq (protein) NP_001159932 NP_032647
Location (UCSC) Chr HG1497_PATCH:
153.99 – 154.03 Mb
Chr X:
75.11 – 75.13 Mb
PubMed search [1] [2]

55 kDa erythrocyte membrane protein is a protein that in humans is encoded by the MPP1 gene.[1][2]

Palmitoylated membrane protein 1 is the prototype of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 1 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction.[2]


Further reading[edit]