MPP5

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Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
Protein MPP5 PDB 1va8.png
PDB rendering based on 1va8.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols MPP5 ; PALS1
External IDs OMIM606958 MGI1927339 HomoloGene9512 GeneCards: MPP5 Gene
RNA expression pattern
PBB GE MPP5 219321 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 64398 56217
Ensembl ENSG00000072415 ENSMUSG00000021112
UniProt Q8N3R9 Q9JLB2
RefSeq (mRNA) NM_001256550 NM_019579
RefSeq (protein) NP_001243479 NP_062525
Location (UCSC) Chr 14:
67.71 – 67.8 Mb
Chr 12:
78.75 – 78.84 Mb
PubMed search [1] [2]

MAGUK p55 subfamily member 5 is a protein that in humans is encoded by the MPP5 gene.[1][2]

Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains (Tseng et al., 2001). MPP5 is a member of the p55-like MAGUK subfamily.[supplied by OMIM][2]

Interactions[edit]

MPP5 has been shown to interact with INADL.[1]

References[edit]

Further reading[edit]