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MPV may refer to:
- Multi-Purpose Viewer, an open-source, cross platform image generator
- MPV can be a file format, used by MP4 players
- mpv player, an open source audio and video player; see MPlayer#Forks
- Mean platelet volume, a measurement of the average size of platelets found in blood
- Multi-Purpose Vehicle, a type of automobile known in North America as a minivan
- Windhoff MPV, a rail vehicle used for rail infrastructure maintenance and other work
- British Rail MPV, a version of the Windoff MPV used in the United Kingdom
- M.P. Vijay Kumar, member of the Institute of Chartered Accountants of India, based in Chennai
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