Myosin is a major contractile protein that converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals, at least ten different myosin heavy chain (MYH) isoforms have been described from striated, smooth, and nonmuscle cells. These isoforms show expression that is spatially and temporally regulated during development.
Smerdu V, Karsch-Mizrachi I, Campione M, et al. (1995). "Type IIx myosin heavy chain transcripts are expressed in type IIb fibers of human skeletal muscle". Am. J. Physiol.267 (6 Pt 1): C1723–8. PMID7545970.
Weiss A, Schiaffino S, Leinwand LA (1999). "Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity". J. Mol. Biol.290 (1): 61–75. doi:10.1006/jmbi.1999.2865. PMID10388558.
Daugaard JR, Nielsen JN, Kristiansen S, et al. (2000). "Fiber type-specific expression of GLUT4 in human skeletal muscle: influence of exercise training". Diabetes49 (7): 1092–5. doi:10.2337/diabetes.49.7.1092. PMID10909963.
Korfage JA, Brugman P, Van Eijden TM (2000). "Intermuscular and intramuscular differences in myosin heavy chain composition of the human masticatory muscles". J. Neurol. Sci.178 (2): 95–106. doi:10.1016/S0022-510X(00)00372-5. PMID11018701.
Konig S, Burkman J, Fitzgerald J, et al. (2002). "Modular organization of phylogenetically conserved domains controlling developmental regulation of the human skeletal myosin heavy chain gene family". J. Biol. Chem.277 (31): 27593–605. doi:10.1074/jbc.M203162200. PMID11971910.
Pontén EM, Stål PS (2007). "Decreased capillarization and a shift to fast myosin heavy chain IIx in the biceps brachii muscle from young adults with spastic paresis". J. Neurol. Sci.253 (1–2): 25–33. doi:10.1016/j.jns.2006.11.006. PMID17196619.