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Myosin, light chain 1, alkali; skeletal, fast
Symbols MYL1 ; MLC1F; MLC3F
External IDs OMIM160780 MGI97269 HomoloGene23194 GeneCards: MYL1 Gene
RNA expression pattern
PBB GE MYL1 209888 s at tn.png
More reference expression data
Species Human Mouse
Entrez 4632 17901
Ensembl ENSG00000168530 ENSMUSG00000061816
UniProt P05976 P05977
RefSeq (mRNA) NM_079420 NM_001113387
RefSeq (protein) NP_524144 NP_001106858
Location (UCSC) Chr 2:
211.15 – 211.18 Mb
Chr 1:
66.92 – 66.95 Mb
PubMed search [1] [2]

Myosin light chain 3, skeletal muscle isoform is a protein that in humans is encoded by the MYL1 gene.[1][2][3]

Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in fast skeletal muscle. Two transcript variants have been identified for this gene.[3]


  1. ^ Hailstones DL, Gunning PW (Mar 1990). "Characterization of human myosin light chains 1sa and 3nm: implications for isoform evolution and function". Mol Cell Biol 10 (3): 1095–104. PMC 360973. PMID 2304459. 
  2. ^ Cohen-Haguenauer O, Barton PJ, Nguyen VC, Serero S, Gross MS, Jegou-Foubert C, de Tand MF, Robert B, Buckingham M, Frezal J (Mar 1988). "Assignment of the human fast skeletal muscle myosin alkali light chains gene (MLC1F/MLC3F) to 2q 32.1-2qter". Hum Genet 78 (1): 65–70. doi:10.1007/BF00291237. PMID 3422212. 
  3. ^ a b "Entrez Gene: MYL1 myosin, light chain 1, alkali; skeletal, fast". 

Further reading[edit]