Magnesium L-threonate

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Magnesium L-threonate
Identifiers
CAS number 778571-57-6 YesY
500304-76-7 (hydrate)
Jmol-3D images Image 1
Properties
Molecular formula C8H14MgO10
Molar mass 294.5 g mol−1
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Magnesium L-threonate is a magnesium salt of L-threonic acid having the formula Mg(C4H7O5)2.[1]

One study reported that magnesium L-threonate administered to rats significantly boosts their cognitive abilities[2] [3], and suggest that the same effect may occur in humans, although this remains to be tested. Another study suggests that because L-threonate inhibited DKK-1 expression, it may have application as a treatment for the prevention of androgen-driven balding[4]

[edit] References

  1. ^ Gao Sheng-Li;Yang Xu-Wu;Chen San-Ping;Ju Zhan-Feng (2002). "Synthesis and Standard Enthalpy of Formation of Magnesium L-Threonate". Acta Phys. -Chim. Sin. 18 (11): 994–997. http://www.whxb.pku.edu.cn/EN/abstract/abstract24156.shtml. 
  2. ^ Magnesium Supplement Helps Boost Brainpower, Science Daily, Feb. 2, 2010
  3. ^ Inna Slutsky, Nashat Abumaria, Long-Jun Wu, Chao Huang, Ling Zhang, Bo Li, Xiang Zhao, Arvind Govindarajan, Ming-Gao Zhao, Min Zhuo, Susumu Tonegawa, and Guosong Liu (2010). "Enhancement of Learning and Memory by Elevating Brain Magnesium". Neuron 65 (2): 165–177. doi:10.1016/j.neuron.2009.12.026. PMID 20152124. http://www.cell.com/neuron/abstract/S0896-6273(09)01044-7. 
  4. ^ Kwack MH, Ahn JS, Kim MK, Kim JC, Sung YK. Preventable effect of L-threonate, an ascorbate metabolite, on androgen-driven balding via repression of dihydrotestosterone-induced dickkopf-1 expression in human hair dermal papilla cells. BMB Rep. 2010 Oct;43(10):688-92 PMID 21034532 http://www.bmbreports.org/fulltext/bmbreports/view.php?vol=43&page=688


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