Masri was born in Amman, Jordan on April 2, 1959. She is the daughter of Munib Masri from Nablus and an American mother from Texas. Masri was raised in Beirut, where she has lived most of her life. She graduated from San Francisco State University in 1981. Soon after that she returned to Beirut and began making films.
Masri met her husband, Lebanese filmmaker Jean Chamoun, in 1982. They have made several films together. They married in 1986, and have two daughters, Nour and Hana. Nour is an interaction designer, and Hana is currently studying communication arts. Mai was living near the Palestinian refugee camp of Shatila in Beirut when the Lebanese Phalangist militia carried out massacre and rape in 1982.
- Under the Rubble (1983)
- Wild Flowers: Women of South Lebanon (1986)
- War Generation (1989)
- Children of Fire (1990)
- Suspended Dreams (1992)
- Hanan Ashrawi: A Woman of Her Time (1995)
- Children of Shatila (1998)
- Frontiers of Dreams and Fears (2001)
- Beirut Diaries (2006)
- 33 Days (2007)
- Masri, Mai. (January 2008) "Transcending Boundaries", This Week in Palestine.
- Mai Masri at IMDb
- Mai Masri at "Dreams of a Nation", Columbia University
- Dubai Women's College biography
- Mai Masri Palestinian Filmmaker
- Zenith Foundation website
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