Makedonska Kamenica (Macedonian: Македонска Каменица) is a municipality in eastern Republic of Macedonia. Makedonska Kamenica is also the name of the town where the municipal seat is found. The municipality is part of Eastern Statistical Region.
The municipality borders Kriva Palanka Municipality in the north, Bulgaria and Delčevo Municipality to the east, Kočani Municipality to the west, and Vinica Municipality to the west.
Makedonska Kamenica Municipality had 8,110 residents at the 2002 Macedonian census. Ethnic groups in the municipality:
- Macedonians = 8,055 (99.3%)
- others = 55
|Demographics of Makedonska Kamenica municipality
Inhabited places 
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Coordinates: 42°01′N 22°35′E / 42.01°N 22.58°E