Malcolm Clive Spence (4 September 1937 – 30 December 2010) was a South Africanathlete who competed mainly in the 400 metres. All sixteen of Malcolm Spence's great, great grandparents emigrated to South Africa from Kent, England.
He ran for South Africa in the 1956 Summer Olympics held in Melbourne, Australia, finishing sixth in the 400 meters. In the 1958 Commonwealth Games he won silver in the individual and gold in the relay. He also represented his country in the 400 metres in the 1960 Summer Olympics held in Rome, Italy, where he won the bronze medal.