In anesthesia, the Mallampati score, also Mallampati classification, is used to predict the ease of intubation. A high Mallampati score (class 3 or 4) is associated with more difficult intubation as well as a higher incidence of sleep apnea.
The Mallampati score is assessed by asking the patient (in a sitting posture) to open his/her mouth and protrude the tongue as much as possible. The anatomy of the oral cavity is visualized; specifically, whether the base of the uvula, faucial pillars (the arches in front of and behind the tonsils) and soft palate are visible. Scoring may be done with or without phonation. Depending on whether the tongue is maximally protruded and/or the patient asked to phonate, the scoring may vary.
Modified Mallampati Scoring:
- Class I: Soft palate, uvula, fauces, pillars visible.
- Class II: Soft palate, uvula, fauces visible.
- Class III: Soft palate, base of uvula visible.
- Class IV: Only hard palate visible
Original Mallampati Scoring:
- Class 1: Faucial pillars, soft palate and uvula could be visualized.
- Class 2: Faucial pillars and soft palate could be visualized, but uvula was masked by the base of the tongue.
- Class 3: Only soft palate visualized.
Further research may be needed to determine the most effective consistent and predictive approach on which to standardize Mallampati Scoring.
Clinical significance 
While Mallampati classes I and II are associated with relatively easy intubation, classes III and IV are associated with increased difficulty.
A systematic review of 42 studies, with 34,513 participants, found that the modified Mallampati score is a good predictor of difficult direct laryngoscopy and intubation, but poor at predicting difficult bag mask ventilation. Therefore, the study concluded that while useful in combination with other tests to predict the difficulty of an airway, it is not suffiently accurate alone.
- Mallampati, S. R.; Gatt, S. P.; Gugino, L. D.; Desai, S. P.; Waraksa, B.; Freiberger, D.; Liu, P. L. (1985). "A clinical sign to predict difficult tracheal intubation: A prospective study". Canadian Anaesthetists' Society journal 32 (4): 429–434. doi:10.1007/BF03011357. PMID 4027773.
- Nuckton TJ, Glidden DV, Browner WS, Claman DM (Jul 1, 2006). "Physical examination: Mallampati score as an independent predictor of obstructive sleep apnea". Sleep 29 (7): 903–8. PMID 16895257.
- Samsoon, GL; Young, JR (May 1987). "Difficult tracheal intubation: a retrospective study.". Anaesthesia 42 (5): 487–90. PMID 3592174.
- Lee, A.; Fan, L. T. Y.; Gin, T.; Karmakar, M. K.; Ngan Kee, W. D. (2006). "A Systematic Review (Meta-Analysis) of the Accuracy of the Mallampati Tests to Predict the Difficult Airway". Anesthesia & Analgesia 102 (6): 1867–1878. doi:10.1213/01.ane.0000217211.12232.55. PMID 16717341.