Maltose phosphorylase

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maltose phosphorylase
Identifiers
EC number 2.4.1.8
CAS number 9030-19-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a maltose phosphorylase (EC 2.4.1.8) is an enzyme that catalyzes the chemical reaction

maltose + phosphate \rightleftharpoons D-glucose + beta-D-glucose 1-phosphate

Thus, the two substrates of this enzyme are maltose and phosphate, whereas its two products are D-glucose and beta-D-glucose 1-phosphate.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is maltose:phosphate 1-beta-D-glucosyltransferase. This enzyme participates in starch and sucrose metabolism.

Structural studies[edit]

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1H54.

References[edit]

  • Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 5, Academic Press, New York, 1961, p. 229-236.
  • FITTING C, DOUDOROFF M (1952). "Phosphorolysis of maltose by enzyme preparations from Neisseria meningitidis". J. Biol. Chem. 199 (1): 153–63. PMID 12999827. 
  • Putman EW, Litt CF and Hassid WZ (1955). "The structure of D-glucose-D-xylose synthesized by maltose phosphorylase". J. Am. Chem. Soc. 77 (16): 4351–4353. doi:10.1021/ja01621a050. 
  • Wood BJB and Rainbow C (1961). "The maltophosphorylase of beer lactobacilli". Biochem. J. 78: 204–209. PMC 1205197. PMID 13786484.