Mani graduated as an Chemical Engineer from BITS Pilani and has done pioneering work in film special effects for his first two films which got him several nominations as best visual effect supervisor. His films carry a unique signature style and pace. Mani has also made over 1000 ad films and short films. His noteworthy short films include special films made for the Government of Andhra Pradesh to commemorate the Indian visits of two U.S. Presidents, Bill Clinton and George H. W. Bush.
16 December was a huge hit and was among the top ten grossers of 2002. He has won several awards and nominations including the Golden Nandi award as well as Star Screen nominations for Best Director, Best Screenplay Writer and Best Visual Effects Supervisor. Mukhbir received positive reviews and was screened at the Black International Film festival at Berlin. Tango Charlie was critically acclaimed and was part of Amnesty International's collection of anti war films, but failed at the box office. Knock Out, his most recent film was an unauthorized remake of Phone Booth. The film was a disaster at the Indian box office and was not well received by critics.