Manuel Elkin Patarroyo

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This name uses Spanish naming customs; the first or paternal family name is Patarroyo and the second or maternal family name is Murillo.
Manuel Elkin Patarroyo
Patarroyo.jpg
Born Manuel Elkin Patarroyo Murillo
(1946-03-11) March 11, 1946 (age 68)
Ataco, Tolima, Colombia
Education National University of Colombia (MD)
Rockefeller University (Ph.D)
Known for Malaria license
Medical career
Profession Doctor
Institutions Hospital San Juan de Dios, Bogota, National University of Colombia
Specialism Pathologist
Research Immunology
Notable prizes Prince of Asturias Awards (1994)

Manuel Elkin Patarroyo (born March 11, 1946)[1] is a Colombian pathologist who made the world's first attempt to create a synthetic vaccine for malaria,[2] a disease transmitted by mosquitoes that affects millions of people in tropical and subtropical regions, including parts of the Americas, Asia, and Africa. The vaccine candidate, first developed in 1987, was evaluated in clinical trials carried out by the WHO in Gambia, Tanzania and Thailand, and had mixed results.[3] In 2009, a comprehensive Cochrane review assessed the SPf66 as being not efficacious in Africa and Asia, and as having a low but statistically significant efficacy of 28% in South America.[4] Today, after more than 33 years of research, there is still however "no licensed malaria vaccine. Researchers, clinical trialists and vaccine developers have been working on many approaches to bring forward the availability of a malaria vaccine."[5] More research and clinical trials are required for a universal vaccine to be implemented.

References[edit]

  1. ^ Fundación Príncipe de Asturias. Manuel Elkin Patarroyo (Spanish). Premiados, Investigación Científica y Técnica, 1994.
  2. ^ Holloway, M. (1996) Profile: Manuel Elkin Patarroyo – The Man Who Would Conquer Malaria, Scientific American 275(6), 52-56.
  3. ^ - Susan Aldridge, Magic Molecules: How Drugs Work (Cambridge University Press, 1998), p. 89
  4. ^ - Graves, P. M. and Gelband, H. (2009) Vaccines for preventing malaria (SPf66) (Review), The Cochrane Library 2009, (2), pp.1-38.
  5. ^ - WHO (2010) Tables of Malaria Vaccine Projects Globally (Updated December 2010), Initiative for Vaccine Research.

External links[edit]