Margaret Mazzantini (born 27 October 1961) is an Italian writer and actress. She became a film, television and stage actor, but is best known as a writer. Mazzantini began her acting career in 1980 starring in the cult horror classic Antropophagus, she has also appeared in television and theatre. As a successful writer her novels include Non ti muovere (Don't Move) which was adapted into a film of the same name and is directed by her husband Sergio Castellitto and stars Penélope Cruz. Her career as a writer and actress has earned her several awards and nominations including Campiello Awards, a Golden Ticket Award, and a Goya Award.
Mazzantini was born in Dublin, Ireland to Carlo Mazzantini, an Italian writer and artist, and Anne Donnelly, an Irish artist. She spent her childhood around Europe, Spain, and Tangier, until the family settled in Tivoli. In 1982 she graduated from the Academy of Dramatic Arts in Rome.