Marginal nucleus of spinal cord

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Brain: Posteromarginal nucleus
Medulla spinalis - Substantia grisea - English.svg
Medulla spinalis (Rexed lamina I labeled at upper left.)
Latin Nucleus marginalis medullae spinalis, lamina spinalis I
NeuroNames ancil-984

The marginal nucleus of spinal cord, or posteromarginal nucleus, or Substantia Marginalis, Rexed lamina I, is located at the most dorsal aspect of the dorsal horn of the spinal cord. The neurons located here receive input primarily from Lissauer's tract and relay information related to pain and temperature sensation. Pain sensation relayed here cannot be modulated, e.g. pain from burning the skin.