Marie Mullen (born 1953) is an Irish actress and co-founder of the Druid Theatre Company.
Mullen acted in DruidSynge, a theatre production of the complete plays of John Millington Synge, performed in the same day, by the Druid Theatre Company in which she played parts in five of the six plays. Mullen won the 1998 Tony Award for Best Actress in a play for The Beauty Queen of Leenane. In 2007, she performed alongside James Cromwell in the Druid production of Long Day's Journey into Night.
Mullen was married to Irish actor Seán McGinley and they have two children. Her husband has been associated with the Druid Theatre Company many times in the past.