She had two sisters, Charlotte de Valois (1446–1477) and Jeanne de Valois (born 1448).
Marie married Olivier de Coétivy, Count of Taillebourg. Her older sister Charlotte married Jacques de Brézé, Count of Maulevrier, and mothered Louis de Brézé, seigneur d'Anet, husband of Diane de Poitiers. Allegedly Charlotte was killed by her husband for having committed adultery. Jeanne married Antoine de Bueil, Count of Sancerre.