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CAS number 470-42-8 YesY
PubChem 11969465
ChemSpider 10142870
Jmol-3D images Image 1
Molecular formula C24H32O5
Molar mass 400.51 g mol−1
Main hazards Toxic
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

Marinobufagenin (marinobufagin) is a cardiotonic bufadienolide steroid secreted by the toad Bufo rubescens[1] and other related species such as Bufo marinus. It is a vasoconstrictor with effects similar to digitalis.[2]


  1. ^ Cunha Filho, GA; Schwartz, CA; Resck, IS; Murta, MM; Lemos, SS; Castro, MS; Kyaw, C; Pires Jr, OR et al. (2005). "Antimicrobial activity of the bufadienolides marinobufagin and telocinobufagin isolated as major components from skin secretion of the toad Bufo rubescens". Toxicon : official journal of the International Society on Toxinology 45 (6): 777–82. doi:10.1016/j.toxicon.2005.01.017. PMID 15804527. 
  2. ^ Fedorova, OV; Talan, MI; Agalakova, NI; Lakatta, EG; Bagrov, AY (2002). "Endogenous ligand of alpha(1) sodium pump, marinobufagenin, is a novel mediator of sodium chloride--dependent hypertension". Circulation 105 (9): 1122–7. doi:10.1161/hc0902.104710. PMID 11877366.