Maropitant

Maropitant

Systematic (IUPAC) name
(7R,8S)-N-[(5-tert-Butyl-2-methoxyphenyl)methyl]-7-[di(phenyl)methyl]-1-azabicyclo[2.2.2]octan-8-amine
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	veterinary prescription only
Routes	Oral, subcutaneous
Identifiers
ATCvet code	QA04AD90
PubChem	CID 23724948
ChemSpider	176804 Y
UNII	4XE2T9H4DH Y
Chemical data
Formula	C32H40N2O
Mol. mass	468.67 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C32H40N2O.C6H8O7.H2O/c1-32(2,3)27-15-16-28(35-4)26(21-27)22-33-30-25-17-19-34(20-18-25)31(30)29(23-11-7-5-8-12-23)24-13-9-6-10-14-24;7-3(8)1-6(13,5(11)12)2-4(9)10;/h5-16,21,25,29-31,33H,17-20,22H2,1-4H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);1H2/t30-,31-;;/m0../s1 Y Key:PGVSXRHFXJOMGW-YBZGWEFGSA-N Y
Y (what is this?)  (verify)

Maropitant (trade name Cerenia in the US and other countries), used as maropitant citrate (USAN), is a neurokinin (NK₁) receptor antagonist, which was developed by Pfizer Animal Health specifically for the treatment of motion sickness and vomiting in dogs. It has been approved by the FDA in 2007 for use in dogs, but not for any other animal.

See also

• L-733,060